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Activation of Cryptic Antibiotic Biosynthetic Gene Clusters Guided by RNA-seq Data from Both Streptomyces ansochromogenes and ΔwblA

With the increase of drug resistance caused by the improper use and abuse of antibiotics, human beings are facing a global health crisis. Sequencing of Streptomyces genomes revealed the presence of an important reservoir of secondary metabolic gene clusters for previously unsuspected products with p...

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Detalles Bibliográficos
Autores principales: Li, Yue, Yu, Haiying, Guan, Hanye, Li, Jingjing, Zhang, Jihui, Xiang, Hua, Li, Jine, Tan, Huarong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465540/
https://www.ncbi.nlm.nih.gov/pubmed/34572679
http://dx.doi.org/10.3390/antibiotics10091097