Whey-Derived Porous Carbon Scaffolds for Bone Tissue Engineering

Porous carbon structures derived from whey powders are described and evaluated as potential scaffolds in bone tissue engineering. These materials have a porosity between 48% and 58%, with a hierarchical pore size distribution ranging from 1 to 400 micrometres. Compressive strength and elastic modulu...

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Detalles Bibliográficos
Autores principales: Llamas-Unzueta, Raúl, Suárez, Marta, Fernández, Adolfo, Díaz, Raquel, Montes-Morán, Miguel A., Menéndez, J. Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465549/
https://www.ncbi.nlm.nih.gov/pubmed/34572276
http://dx.doi.org/10.3390/biomedicines9091091
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author Llamas-Unzueta, Raúl
Suárez, Marta
Fernández, Adolfo
Díaz, Raquel
Montes-Morán, Miguel A.
Menéndez, J. Angel
author_facet Llamas-Unzueta, Raúl
Suárez, Marta
Fernández, Adolfo
Díaz, Raquel
Montes-Morán, Miguel A.
Menéndez, J. Angel
author_sort Llamas-Unzueta, Raúl
collection PubMed
description Porous carbon structures derived from whey powders are described and evaluated as potential scaffolds in bone tissue engineering. These materials have a porosity between 48% and 58%, with a hierarchical pore size distribution ranging from 1 to 400 micrometres. Compressive strength and elastic modulus are outstanding for such a porous material, being up to three times better than those of traditional HA or TCP scaffolds with similar porosities. They also present non-cytotoxic and bioactive behavior, due to their carbon-based composition that also includes some residual mineral salts content.
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spelling pubmed-84655492021-09-27 Whey-Derived Porous Carbon Scaffolds for Bone Tissue Engineering Llamas-Unzueta, Raúl Suárez, Marta Fernández, Adolfo Díaz, Raquel Montes-Morán, Miguel A. Menéndez, J. Angel Biomedicines Article Porous carbon structures derived from whey powders are described and evaluated as potential scaffolds in bone tissue engineering. These materials have a porosity between 48% and 58%, with a hierarchical pore size distribution ranging from 1 to 400 micrometres. Compressive strength and elastic modulus are outstanding for such a porous material, being up to three times better than those of traditional HA or TCP scaffolds with similar porosities. They also present non-cytotoxic and bioactive behavior, due to their carbon-based composition that also includes some residual mineral salts content. MDPI 2021-08-26 /pmc/articles/PMC8465549/ /pubmed/34572276 http://dx.doi.org/10.3390/biomedicines9091091 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Llamas-Unzueta, Raúl
Suárez, Marta
Fernández, Adolfo
Díaz, Raquel
Montes-Morán, Miguel A.
Menéndez, J. Angel
Whey-Derived Porous Carbon Scaffolds for Bone Tissue Engineering
title Whey-Derived Porous Carbon Scaffolds for Bone Tissue Engineering
title_full Whey-Derived Porous Carbon Scaffolds for Bone Tissue Engineering
title_fullStr Whey-Derived Porous Carbon Scaffolds for Bone Tissue Engineering
title_full_unstemmed Whey-Derived Porous Carbon Scaffolds for Bone Tissue Engineering
title_short Whey-Derived Porous Carbon Scaffolds for Bone Tissue Engineering
title_sort whey-derived porous carbon scaffolds for bone tissue engineering
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465549/
https://www.ncbi.nlm.nih.gov/pubmed/34572276
http://dx.doi.org/10.3390/biomedicines9091091
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