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Giant Pulmonary Artery Thrombotic Material, Due to Chronic Thromboembolic Pulmonary Hypertension, Mimics Pulmonary Artery Sarcoma

In this article, we present the case of a 38-year-old female who suffered from serious respiratory distress. After an extensive pulmonary artery imaging diagnostic work-up (CTPA, MRA and PET), we were unable to differentiate between chronic thromboembolic pulmonary hypertension (CTEPH) vs. pulmonary...

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Autores principales: Triantafyllidi, Helen, Iordanidis, Dimitrios, Mpahara, Aikaterini, Mademli, Maria, Birmpa, Dionyssia, Argentos, Stylianos, Benas, Dimitrios, Trivilou, Paraskevi, Anagnostopoulos, Konstantinos, Mayer, Eckhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465601/
https://www.ncbi.nlm.nih.gov/pubmed/34577914
http://dx.doi.org/10.3390/medicina57090992
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author Triantafyllidi, Helen
Iordanidis, Dimitrios
Mpahara, Aikaterini
Mademli, Maria
Birmpa, Dionyssia
Argentos, Stylianos
Benas, Dimitrios
Trivilou, Paraskevi
Anagnostopoulos, Konstantinos
Mayer, Eckhard
author_facet Triantafyllidi, Helen
Iordanidis, Dimitrios
Mpahara, Aikaterini
Mademli, Maria
Birmpa, Dionyssia
Argentos, Stylianos
Benas, Dimitrios
Trivilou, Paraskevi
Anagnostopoulos, Konstantinos
Mayer, Eckhard
author_sort Triantafyllidi, Helen
collection PubMed
description In this article, we present the case of a 38-year-old female who suffered from serious respiratory distress. After an extensive pulmonary artery imaging diagnostic work-up (CTPA, MRA and PET), we were unable to differentiate between chronic thromboembolic pulmonary hypertension (CTEPH) vs. pulmonary artery sarcoma (PAS) due to extensive filling defects and extraluminal findings. Although surgery was postponed for nine months due to the COVID-19 pandemic, CTEPH diagnosis, due to a high-thrombus burden, was finally confirmed after pulmonary endarterectomy (PEA). Conclusively, imaging findings of rare cases of CTEPH might mimic PAS and the surgical removal of the lesion are both needed for a final diagnosis. What is Already Known about This Topic? Pulmonary artery sarcoma (PAS) is a rare but aggressive malignancy, which originates from the intimal layer of the pulmonary artery (PA); Chronic thromboembolic pulmonary hypertension (CTEPH) is based on chronic, organized flow-limiting thrombi inside PA circulation and subsequent pulmonary hypertension. What Does This Study Contribute? Since radiological findings of CTEPH cases might rarely mimic PAS, pulmonary artery endarterectomy and subsequent histopathologic study are needed for a final diagnosis.
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spelling pubmed-84656012021-09-27 Giant Pulmonary Artery Thrombotic Material, Due to Chronic Thromboembolic Pulmonary Hypertension, Mimics Pulmonary Artery Sarcoma Triantafyllidi, Helen Iordanidis, Dimitrios Mpahara, Aikaterini Mademli, Maria Birmpa, Dionyssia Argentos, Stylianos Benas, Dimitrios Trivilou, Paraskevi Anagnostopoulos, Konstantinos Mayer, Eckhard Medicina (Kaunas) Case Report In this article, we present the case of a 38-year-old female who suffered from serious respiratory distress. After an extensive pulmonary artery imaging diagnostic work-up (CTPA, MRA and PET), we were unable to differentiate between chronic thromboembolic pulmonary hypertension (CTEPH) vs. pulmonary artery sarcoma (PAS) due to extensive filling defects and extraluminal findings. Although surgery was postponed for nine months due to the COVID-19 pandemic, CTEPH diagnosis, due to a high-thrombus burden, was finally confirmed after pulmonary endarterectomy (PEA). Conclusively, imaging findings of rare cases of CTEPH might mimic PAS and the surgical removal of the lesion are both needed for a final diagnosis. What is Already Known about This Topic? Pulmonary artery sarcoma (PAS) is a rare but aggressive malignancy, which originates from the intimal layer of the pulmonary artery (PA); Chronic thromboembolic pulmonary hypertension (CTEPH) is based on chronic, organized flow-limiting thrombi inside PA circulation and subsequent pulmonary hypertension. What Does This Study Contribute? Since radiological findings of CTEPH cases might rarely mimic PAS, pulmonary artery endarterectomy and subsequent histopathologic study are needed for a final diagnosis. MDPI 2021-09-20 /pmc/articles/PMC8465601/ /pubmed/34577914 http://dx.doi.org/10.3390/medicina57090992 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Triantafyllidi, Helen
Iordanidis, Dimitrios
Mpahara, Aikaterini
Mademli, Maria
Birmpa, Dionyssia
Argentos, Stylianos
Benas, Dimitrios
Trivilou, Paraskevi
Anagnostopoulos, Konstantinos
Mayer, Eckhard
Giant Pulmonary Artery Thrombotic Material, Due to Chronic Thromboembolic Pulmonary Hypertension, Mimics Pulmonary Artery Sarcoma
title Giant Pulmonary Artery Thrombotic Material, Due to Chronic Thromboembolic Pulmonary Hypertension, Mimics Pulmonary Artery Sarcoma
title_full Giant Pulmonary Artery Thrombotic Material, Due to Chronic Thromboembolic Pulmonary Hypertension, Mimics Pulmonary Artery Sarcoma
title_fullStr Giant Pulmonary Artery Thrombotic Material, Due to Chronic Thromboembolic Pulmonary Hypertension, Mimics Pulmonary Artery Sarcoma
title_full_unstemmed Giant Pulmonary Artery Thrombotic Material, Due to Chronic Thromboembolic Pulmonary Hypertension, Mimics Pulmonary Artery Sarcoma
title_short Giant Pulmonary Artery Thrombotic Material, Due to Chronic Thromboembolic Pulmonary Hypertension, Mimics Pulmonary Artery Sarcoma
title_sort giant pulmonary artery thrombotic material, due to chronic thromboembolic pulmonary hypertension, mimics pulmonary artery sarcoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465601/
https://www.ncbi.nlm.nih.gov/pubmed/34577914
http://dx.doi.org/10.3390/medicina57090992
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