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A Small Virus to Deliver Small Antibodies: New Targeted Therapies Based on AAV Delivery of Nanobodies

Nanobodies are camelid-derived single-domain antibodies that present some advantages versus conventional antibodies, such as a smaller size, and higher tissue penetrability, stability, and hydrophilicity. Although nanobodies can be delivered as proteins, in vivo expression from adeno-associated vira...

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Detalles Bibliográficos
Autores principales: Silva-Pilipich, Noelia, Smerdou, Cristian, Vanrell, Lucía
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465657/
https://www.ncbi.nlm.nih.gov/pubmed/34576851
http://dx.doi.org/10.3390/microorganisms9091956

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