Cargando…
Suggested Reference Ranges of Blood Mg and Ca Level in Childbearing Women of China: Analysis of China Adult Chronic Disease and Nutrition Surveillance (2015)
Background: Magnesium and calcium play a variety of biological roles in body functions. Reference values of these elements have not yet been systematically determined in China, especially in childbearing women. We proposed to establish the reference range of Mg, Ca, and Ca/Mg ratio in plasma and who...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465667/ https://www.ncbi.nlm.nih.gov/pubmed/34579161 http://dx.doi.org/10.3390/nu13093287 |
_version_ | 1784572934779568128 |
---|---|
author | Zhang, Huidi Cao, Yang Song, Pengkun Man, Qingqing Mao, Deqian Hu, Yichun Yang, Lichen |
author_facet | Zhang, Huidi Cao, Yang Song, Pengkun Man, Qingqing Mao, Deqian Hu, Yichun Yang, Lichen |
author_sort | Zhang, Huidi |
collection | PubMed |
description | Background: Magnesium and calcium play a variety of biological roles in body functions. Reference values of these elements have not yet been systematically determined in China, especially in childbearing women. We proposed to establish the reference range of Mg, Ca, and Ca/Mg ratio in plasma and whole blood for 18–44 years healthy childbearing women in China. Method: A total of 1921 women of childbearing age (18–44 years) were randomly selected from the 2015 China National Nutrition and Health Survey by taking into account the regional types and monitoring points. Among them, 182 healthy women were screened out with a series strict inclusion criteria to study the reference ranges of elements. Fundamental indicators (weight, height, waist, blood pressure, total cholesterol, triglyceride, high-density lipoprotein cholesterol, low-density lipoprotein, fast glucose, HbA1c, blood pressure, uric acid) and elements concentrations in plasma and whole blood were collected. The 2.5th to 97.5th was used to represent the reference range of Mg, Ca, and Ca/Mg ratio. Results: The reference range of Mg, Ca, and Ca/Mg ratio in plasma were 0.75–1.13 mmol/L, 2.27–3.43 mmol/L, and 2.41–3.44, respectively. Additionally, the reference range of Mg, Ca, and Ca/Mg ratio in whole blood were 1.28–1.83 mmol/L, 1.39–2.26 mmol/L, and 0.90–1.66, respectively. According to the established reference range, the prevalence of magnesium deficiency was 4.79% in 1921 childbearing women, 21.05% in type 2 diabetes, and 5.63% in prediabetes. Conclusion: The reference values of Mg, Ca and Ca/Mg proportion in plasma and entire blood of healthy childbearing women can be utilized as a pointer to assess the status of component lack and over-burden. The lower limit of plasma Mg is in good agreement with the recommended criteria for the determination of hypomagnesemia. |
format | Online Article Text |
id | pubmed-8465667 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-84656672021-09-27 Suggested Reference Ranges of Blood Mg and Ca Level in Childbearing Women of China: Analysis of China Adult Chronic Disease and Nutrition Surveillance (2015) Zhang, Huidi Cao, Yang Song, Pengkun Man, Qingqing Mao, Deqian Hu, Yichun Yang, Lichen Nutrients Article Background: Magnesium and calcium play a variety of biological roles in body functions. Reference values of these elements have not yet been systematically determined in China, especially in childbearing women. We proposed to establish the reference range of Mg, Ca, and Ca/Mg ratio in plasma and whole blood for 18–44 years healthy childbearing women in China. Method: A total of 1921 women of childbearing age (18–44 years) were randomly selected from the 2015 China National Nutrition and Health Survey by taking into account the regional types and monitoring points. Among them, 182 healthy women were screened out with a series strict inclusion criteria to study the reference ranges of elements. Fundamental indicators (weight, height, waist, blood pressure, total cholesterol, triglyceride, high-density lipoprotein cholesterol, low-density lipoprotein, fast glucose, HbA1c, blood pressure, uric acid) and elements concentrations in plasma and whole blood were collected. The 2.5th to 97.5th was used to represent the reference range of Mg, Ca, and Ca/Mg ratio. Results: The reference range of Mg, Ca, and Ca/Mg ratio in plasma were 0.75–1.13 mmol/L, 2.27–3.43 mmol/L, and 2.41–3.44, respectively. Additionally, the reference range of Mg, Ca, and Ca/Mg ratio in whole blood were 1.28–1.83 mmol/L, 1.39–2.26 mmol/L, and 0.90–1.66, respectively. According to the established reference range, the prevalence of magnesium deficiency was 4.79% in 1921 childbearing women, 21.05% in type 2 diabetes, and 5.63% in prediabetes. Conclusion: The reference values of Mg, Ca and Ca/Mg proportion in plasma and entire blood of healthy childbearing women can be utilized as a pointer to assess the status of component lack and over-burden. The lower limit of plasma Mg is in good agreement with the recommended criteria for the determination of hypomagnesemia. MDPI 2021-09-20 /pmc/articles/PMC8465667/ /pubmed/34579161 http://dx.doi.org/10.3390/nu13093287 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Zhang, Huidi Cao, Yang Song, Pengkun Man, Qingqing Mao, Deqian Hu, Yichun Yang, Lichen Suggested Reference Ranges of Blood Mg and Ca Level in Childbearing Women of China: Analysis of China Adult Chronic Disease and Nutrition Surveillance (2015) |
title | Suggested Reference Ranges of Blood Mg and Ca Level in Childbearing Women of China: Analysis of China Adult Chronic Disease and Nutrition Surveillance (2015) |
title_full | Suggested Reference Ranges of Blood Mg and Ca Level in Childbearing Women of China: Analysis of China Adult Chronic Disease and Nutrition Surveillance (2015) |
title_fullStr | Suggested Reference Ranges of Blood Mg and Ca Level in Childbearing Women of China: Analysis of China Adult Chronic Disease and Nutrition Surveillance (2015) |
title_full_unstemmed | Suggested Reference Ranges of Blood Mg and Ca Level in Childbearing Women of China: Analysis of China Adult Chronic Disease and Nutrition Surveillance (2015) |
title_short | Suggested Reference Ranges of Blood Mg and Ca Level in Childbearing Women of China: Analysis of China Adult Chronic Disease and Nutrition Surveillance (2015) |
title_sort | suggested reference ranges of blood mg and ca level in childbearing women of china: analysis of china adult chronic disease and nutrition surveillance (2015) |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465667/ https://www.ncbi.nlm.nih.gov/pubmed/34579161 http://dx.doi.org/10.3390/nu13093287 |
work_keys_str_mv | AT zhanghuidi suggestedreferencerangesofbloodmgandcalevelinchildbearingwomenofchinaanalysisofchinaadultchronicdiseaseandnutritionsurveillance2015 AT caoyang suggestedreferencerangesofbloodmgandcalevelinchildbearingwomenofchinaanalysisofchinaadultchronicdiseaseandnutritionsurveillance2015 AT songpengkun suggestedreferencerangesofbloodmgandcalevelinchildbearingwomenofchinaanalysisofchinaadultchronicdiseaseandnutritionsurveillance2015 AT manqingqing suggestedreferencerangesofbloodmgandcalevelinchildbearingwomenofchinaanalysisofchinaadultchronicdiseaseandnutritionsurveillance2015 AT maodeqian suggestedreferencerangesofbloodmgandcalevelinchildbearingwomenofchinaanalysisofchinaadultchronicdiseaseandnutritionsurveillance2015 AT huyichun suggestedreferencerangesofbloodmgandcalevelinchildbearingwomenofchinaanalysisofchinaadultchronicdiseaseandnutritionsurveillance2015 AT yanglichen suggestedreferencerangesofbloodmgandcalevelinchildbearingwomenofchinaanalysisofchinaadultchronicdiseaseandnutritionsurveillance2015 |