Genetic and Epigenetic Characterization of a Discordant KMT2A/AFF1-Rearranged Infant Monozygotic Twin Pair

The KMT2A/AFF1 rearrangement is associated with an unfavorable prognosis in infant acute lymphocytic leukemia (ALL). Discordant ALL in monozygotic twins is uncommon and represents an attractive resource to evaluate intrauterine environment–genetic interplay in ALL. Mutational and epigenetic profiles...

Descripción completa

Detalles Bibliográficos
Autores principales: Russo, Alessia, Viberti, Clara, Mareschi, Katia, Casalone, Elisabetta, Guarrera, Simonetta, Birolo, Giovanni, Cazzaniga, Giovanni, Corral, Lilia, Trentin, Luca, Basso, Giuseppe, Fagioli, Franca, Matullo, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466096/
https://www.ncbi.nlm.nih.gov/pubmed/34575904
http://dx.doi.org/10.3390/ijms22189740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466096/
https://www.ncbi.nlm.nih.gov/pubmed/34575904
http://dx.doi.org/10.3390/ijms22189740

Ejemplares similares