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The Tumor Microenvironment-Dependent Transcription Factors AHR and HIF-1α Are Dispensable for Leukemogenesis in the Eµ-TCL1 Mouse Model of Chronic Lymphocytic Leukemia
SIMPLE SUMMARY: Chronic lymphocytic leukemia (CLL) is the most common leukemia in Western countries, mostly affecting the elderly. The survival of leukemic cells depends on multiple soluble factors and on the stimulation of the BCR signaling pathway. Microenvironment-dependent transcription factors...
Autores principales: | Gonder, Susanne, Largeot, Anne, Gargiulo, Ernesto, Pierson, Sandrine, Fernandez Botana, Iria, Pagano, Giulia, Paggetti, Jerome, Moussay, Etienne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466120/ https://www.ncbi.nlm.nih.gov/pubmed/34572746 http://dx.doi.org/10.3390/cancers13184518 |
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