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The Tumor Microenvironment-Dependent Transcription Factors AHR and HIF-1α Are Dispensable for Leukemogenesis in the Eµ-TCL1 Mouse Model of Chronic Lymphocytic Leukemia

SIMPLE SUMMARY: Chronic lymphocytic leukemia (CLL) is the most common leukemia in Western countries, mostly affecting the elderly. The survival of leukemic cells depends on multiple soluble factors and on the stimulation of the BCR signaling pathway. Microenvironment-dependent transcription factors...

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Detalles Bibliográficos
Autores principales: Gonder, Susanne, Largeot, Anne, Gargiulo, Ernesto, Pierson, Sandrine, Fernandez Botana, Iria, Pagano, Giulia, Paggetti, Jerome, Moussay, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466120/
https://www.ncbi.nlm.nih.gov/pubmed/34572746
http://dx.doi.org/10.3390/cancers13184518

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