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CD4 T cell help prevents CD8 T cell exhaustion and promotes control of Mycobacterium tuberculosis infection

CD4 T cells are essential for immunity to tuberculosis because they produce cytokines, including interferon-γ. Whether CD4 T cells act as “helper” cells to promote optimal CD8 T cell responses during Mycobacterium tuberculosis is unknown. Using two independent models, we show that CD4 T cell help en...

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Detalles Bibliográficos
Autores principales:	Lu, Yu-Jung, Barreira-Silva, Palmira, Boyce, Shayla, Powers, Jennifer, Cavallo, Kelly, Behar, Samuel M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466141/ https://www.ncbi.nlm.nih.gov/pubmed/34525366 http://dx.doi.org/10.1016/j.celrep.2021.109696

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