Cargando…

C3G Protein, a New Player in Glioblastoma

C3G (RAPGEF1) is a guanine nucleotide exchange factor (GEF) for GTPases from the Ras superfamily, mainly Rap1, although it also acts through GEF-independent mechanisms. C3G regulates several cellular functions. It is expressed at relatively high levels in specific brain areas, playing important role...

Descripción completa

Detalles Bibliográficos
Autores principales:	Manzano, Sara, Gutierrez-Uzquiza, Alvaro, Bragado, Paloma, Cuesta, Angel M, Guerrero, Carmen, Porras, Almudena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466177/ https://www.ncbi.nlm.nih.gov/pubmed/34576182 http://dx.doi.org/10.3390/ijms221810018

Ejemplares similares

C3G downregulation induces the acquisition of a mesenchymal phenotype that enhances aggressiveness of glioblastoma cells
por: Manzano, Sara, et al.
Publicado: (2021)

C3G down-regulation enhances pro-migratory and stemness properties of oval cells by promoting an epithelial-mesenchymal-like process
por: Palao, Nerea, et al.
Publicado: (2022)

C3G Is Upregulated in Hepatocarcinoma, Contributing to Tumor Growth and Progression and to HGF/MET Pathway Activation
por: Sequera, Celia, et al.
Publicado: (2020)

HGK promotes metastatic dissemination in prostate cancer
por: Garcia-Garcia, Sara, et al.
Publicado: (2021)

Centrosome Dynamics and Its Role in Inflammatory Response and Metastatic Process
por: Pancione, Massimo, et al.
Publicado: (2021)

C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38α activation, while it impairs tumor growth through p38α-independent mechanisms
por: Priego, Neibla, et al.
Publicado: (2016)

Germline gain‐of‐function MMP11 variant results in an aggressive form of colorectal cancer
por: Martin‐Morales, Lorena, et al.
Publicado: (2022)

How Rap and its GEFs control liver physiology and cancer development. C3G alterations in human hepatocarcinoma
por: Sequera, Celia, et al.
Publicado: (2018)

Cancer-Associated Fibroblasts in Breast Cancer Treatment Response and Metastasis
por: Fernández-Nogueira, Patricia, et al.
Publicado: (2021)

In vivo production of fluorine-18 in a chicken egg tumor model of breast cancer for proton therapy range verification
por: España, Samuel, et al.
Publicado: (2022)

C3G contributes to platelet activation and aggregation by regulating major signaling pathways
por: Gutiérrez-Herrero, Sara, et al.
Publicado: (2020)

C3G forms complexes with Bcr-Abl and p38α MAPK at the focal adhesions in chronic myeloid leukemia cells: implication in the regulation of leukemic cell adhesion
por: Maia, Vera, et al.
Publicado: (2013)

New functions of C3G in platelet biology: Contribution to ischemia-induced angiogenesis, tumor metastasis and TPO clearance
por: Hernández-Cano, Luis, et al.
Publicado: (2022)

P1348: C3G CONTROLS MEGAKARYOCYTE INFLUENCE ON MYELOID COMMITMENT OF HEMATOPOIETIC STEM CELLS UPON CHEMOTHERAPY-INDUCED MYELOSUPPRESSION.
por: Herranz, Óscar, et al.
Publicado: (2023)

C3G, through its GEF activity, induces megakaryocytic differentiation and proplatelet formation
por: Ortiz-Rivero, Sara, et al.
Publicado: (2018)

C3G promotes a selective release of angiogenic factors from activated mouse platelets to regulate angiogenesis and tumor metastasis
por: Martín-Granado, Víctor, et al.
Publicado: (2017)

Exosome: A New Player in Translational Nanomedicine
por: Aheget, Houssam, et al.
Publicado: (2020)

Proliferation and apoptosis regulation by G protein-coupled estrogen receptor in glioblastoma C6 cells
por: Gutiérrez-Almeida, Coral Estefania, et al.
Publicado: (2022)

Biased G Protein-Coupled Receptor Signaling: New Player in Modulating Physiology and Pathology
por: Bologna, Zuzana, et al.
Publicado: (2017)

G2/M inhibitors as pharmacotherapeutic opportunities for glioblastoma: the old, the new, and the future
por: Castro-Gamero, Angel Mauricio, et al.
Publicado: (2018)

Adhesion G protein-coupled receptors in glioblastoma
por: Stephan, Gabriele, et al.
Publicado: (2021)

Lipid droplets and ferroptosis as new players in brain cancer glioblastoma progression and therapeutic resistance
por: Bezawork-Geleta, Ayenachew, et al.
Publicado: (2022)

Expression and estrogen regulation of G protein-coupled estrogen receptor in human glioblastoma cells
por: Peña-Gutiérrez, Karla Mariana, et al.
Publicado: (2022)

Targeting Protein Kinase C in Glioblastoma Treatment
por: Geribaldi-Doldán, Noelia, et al.
Publicado: (2021)

Health-Related Quality of Life of Latin-American Immigrants and Spanish-Born Attended in Spanish Primary Health Care: Socio-Demographic and Psychosocial Factors
por: Salinero-Fort, Miguel Ángel, et al.
Publicado: (2015)

Oxidized ATM protein kinase is a new signal transduction player that regulates glycolysis in CAFs as well as tumor growth and metastasis
por: Marín-Hernández, Álvaro, et al.
Publicado: (2019)

Biological and Mechanical Synergies to Deal With Proton Therapy Pitfalls: Minibeams, FLASH, Arcs, and Gantryless Rooms
por: Mazal, Alejandro, et al.
Publicado: (2021)

Fused in Liposarcoma Protein, a New Player in the Regulation of HIV-1 Transcription, Binds to Known and Newly Identified LTR G-Quadruplexes
por: Ruggiero, Emanuela, et al.
Publicado: (2022)

Profiling of inhibitory immune checkpoints in glioblastoma: Potential pathogenetic players
por: Lombardo, Salvo Danilo, et al.
Publicado: (2020)

Encopresis /
por: Bragado Alvarez, Carmen
Publicado: (1998)

Effectiveness of Abdominal and Gluteus Medius Training in Lumbo-Pelvic Stability and Adductor Strength in Female Soccer Players. A Randomized Controlled Study
por: Guerrero-Tapia, Héctor, et al.
Publicado: (2021)

Unraveling the role of fibroblasts, FGF5 and FGFR2 in HER2-targeted therapies resistance and tumor progression
por: Bragado, Paloma, et al.
Publicado: (2020)

T Cell Receptor (TCR) Engagement in Apoptosis-defective, but Interleukin 2 (IL-2)–producing, T Cells Results in Impaired ZAP70/CD3-ζ Association
por: Sahuquillo, Almudena G., et al.
Publicado: (1998)

Manipulation of the Plant Host by the Geminivirus AC2/C2 Protein, a Central Player in the Infection Cycle
por: Guerrero, Jennifer, et al.
Publicado: (2020)

Meta-Analysis of RNA-Seq Datasets Identifies Novel Players in Glioblastoma
por: Sallam, Magy, et al.
Publicado: (2022)

Ejercicios para leer correctamente sílabas compuestas
por: Bragado Felices, M. Carmen
Publicado: (1993)

Aprendo a pronunciar la erre : manual práctico para aprender a articular las palabras que contengan la letra r en cualquiera de sus formas.
por: Bragado Felices, Ma. Carmen
Publicado: (1993)

TRIM proteins: New players in virus-induced autophagy
por: Sparrer, Konstantin M. J., et al.
Publicado: (2018)

PLA2G7: a new player in shaping energy metabolism and lifespan
por: Candels, Lena Susanna, et al.
Publicado: (2022)

Dormancy Signatures and Metastasis in Estrogen Receptor Positive and Negative Breast Cancer
por: Kim, Ryung S., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_bq6m6aill2u4fssbn2b5k8lacl