Two Paralogous Gb3/CD77 Synthases in Birds Show Different Preferences for Their Glycoprotein and Glycosphingolipid Substrates

Most glycosyltransferases show remarkable gross and fine substrate specificity, which is reflected in the old one enzyme-one linkage paradigm. While human Gb3/CD77 synthase is a glycosyltransferase that synthesizes the Galα1→4Gal moiety mainly on glycosphingolipids, its pigeon homolog prefers glycop...

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Detalles Bibliográficos
Autores principales: Bereznicka, Anna, Mikolajczyk, Krzysztof, Szymczak-Kulus, Katarzyna, Kapczynska, Katarzyna, Majorczyk, Edyta, Modlinska, Anna, Piasecki, Tomasz, Kaczmarek, Radoslaw, Czerwinski, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466213/
https://www.ncbi.nlm.nih.gov/pubmed/34575935
http://dx.doi.org/10.3390/ijms22189761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466213/
https://www.ncbi.nlm.nih.gov/pubmed/34575935
http://dx.doi.org/10.3390/ijms22189761

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