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Two Paralogous Gb3/CD77 Synthases in Birds Show Different Preferences for Their Glycoprotein and Glycosphingolipid Substrates
Most glycosyltransferases show remarkable gross and fine substrate specificity, which is reflected in the old one enzyme-one linkage paradigm. While human Gb3/CD77 synthase is a glycosyltransferase that synthesizes the Galα1→4Gal moiety mainly on glycosphingolipids, its pigeon homolog prefers glycop...
Autores principales: | Bereznicka, Anna, Mikolajczyk, Krzysztof, Szymczak-Kulus, Katarzyna, Kapczynska, Katarzyna, Majorczyk, Edyta, Modlinska, Anna, Piasecki, Tomasz, Kaczmarek, Radoslaw, Czerwinski, Marcin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466213/ https://www.ncbi.nlm.nih.gov/pubmed/34575935 http://dx.doi.org/10.3390/ijms22189761 |
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