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B Cells and Autoantibodies in AIRE Deficiency

Autoimmune polyendocrine syndrome type 1 (APS-1) is a rare but severe monogenetic autoimmune endocrine disease caused by failure of the Autoimmune Regulator (AIRE). AIRE regulates the negative selection of T cells in the thymus, and the main pathogenic mechanisms are believed to be T cell-mediated,...

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Detalles Bibliográficos
Autores principales:	Wolff, Anette S. B., Braun, Sarah, Husebye, Eystein S., Oftedal, Bergithe E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466229/ https://www.ncbi.nlm.nih.gov/pubmed/34572460 http://dx.doi.org/10.3390/biomedicines9091274

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