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A Diamond-Based Dose-per-Pulse X-ray Detector for Radiation Therapy
One of the goals of modern dynamic radiotherapy treatments is to deliver high-dose values in the shortest irradiation time possible. In such a context, fast X-ray detectors and reliable front-end readout electronics for beam diagnostics are crucial to meet the necessary quality assurance requirement...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466252/ https://www.ncbi.nlm.nih.gov/pubmed/34576426 http://dx.doi.org/10.3390/ma14185203 |
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author | Pettinato, Sara Girolami, Marco Olivieri, Riccardo Stravato, Antonella Caruso, Cristina Salvatori, Stefano |
author_facet | Pettinato, Sara Girolami, Marco Olivieri, Riccardo Stravato, Antonella Caruso, Cristina Salvatori, Stefano |
author_sort | Pettinato, Sara |
collection | PubMed |
description | One of the goals of modern dynamic radiotherapy treatments is to deliver high-dose values in the shortest irradiation time possible. In such a context, fast X-ray detectors and reliable front-end readout electronics for beam diagnostics are crucial to meet the necessary quality assurance requirements of care plans. This work describes a diamond-based detection system able to acquire and process the dose delivered by every single pulse sourced by a linear accelerator (LINAC) generating 6-MV X-ray beams. The proposed system is able to measure the intensity of X-ray pulses in a limited integration period around each pulse, thus reducing the inaccuracy induced by unnecessarily long acquisition times. Detector sensitivity under 6-MV X-photons in the 0.1–10 Gy dose range was measured to be 302.2 nC/Gy at a bias voltage of 10 V. Pulse-by-pulse measurements returned a charge-per-pulse value of 84.68 pC, in excellent agreement with the value estimated (but not directly measured) with a commercial electrometer operating in a continuous integration mode. Significantly, by intrinsically holding the acquired signal, the proposed system enables signal processing even in the millisecond period between two consecutive pulses, thus allowing for effective real-time dose-per-pulse monitoring. |
format | Online Article Text |
id | pubmed-8466252 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-84662522021-09-27 A Diamond-Based Dose-per-Pulse X-ray Detector for Radiation Therapy Pettinato, Sara Girolami, Marco Olivieri, Riccardo Stravato, Antonella Caruso, Cristina Salvatori, Stefano Materials (Basel) Article One of the goals of modern dynamic radiotherapy treatments is to deliver high-dose values in the shortest irradiation time possible. In such a context, fast X-ray detectors and reliable front-end readout electronics for beam diagnostics are crucial to meet the necessary quality assurance requirements of care plans. This work describes a diamond-based detection system able to acquire and process the dose delivered by every single pulse sourced by a linear accelerator (LINAC) generating 6-MV X-ray beams. The proposed system is able to measure the intensity of X-ray pulses in a limited integration period around each pulse, thus reducing the inaccuracy induced by unnecessarily long acquisition times. Detector sensitivity under 6-MV X-photons in the 0.1–10 Gy dose range was measured to be 302.2 nC/Gy at a bias voltage of 10 V. Pulse-by-pulse measurements returned a charge-per-pulse value of 84.68 pC, in excellent agreement with the value estimated (but not directly measured) with a commercial electrometer operating in a continuous integration mode. Significantly, by intrinsically holding the acquired signal, the proposed system enables signal processing even in the millisecond period between two consecutive pulses, thus allowing for effective real-time dose-per-pulse monitoring. MDPI 2021-09-10 /pmc/articles/PMC8466252/ /pubmed/34576426 http://dx.doi.org/10.3390/ma14185203 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Pettinato, Sara Girolami, Marco Olivieri, Riccardo Stravato, Antonella Caruso, Cristina Salvatori, Stefano A Diamond-Based Dose-per-Pulse X-ray Detector for Radiation Therapy |
title | A Diamond-Based Dose-per-Pulse X-ray Detector for Radiation Therapy |
title_full | A Diamond-Based Dose-per-Pulse X-ray Detector for Radiation Therapy |
title_fullStr | A Diamond-Based Dose-per-Pulse X-ray Detector for Radiation Therapy |
title_full_unstemmed | A Diamond-Based Dose-per-Pulse X-ray Detector for Radiation Therapy |
title_short | A Diamond-Based Dose-per-Pulse X-ray Detector for Radiation Therapy |
title_sort | diamond-based dose-per-pulse x-ray detector for radiation therapy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466252/ https://www.ncbi.nlm.nih.gov/pubmed/34576426 http://dx.doi.org/10.3390/ma14185203 |
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