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Proteomics-Based Retinal Target Engagement Analysis and Retina-Targeted Delivery of 17β-Estradiol by the DHED Prodrug for Ocular Neurotherapy in Males

We examined the impact of 17β-estradiol (E2) eye drops on the modulation of the proteome profile in the male rat retina. With discovery-driven proteomics, we have identified proteins that were regulated by our treatment. These proteins were assembled to several bioinformatics-based networks implicat...

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Detalles Bibliográficos
Autores principales:	Prokai-Tatrai, Katalin, Zaman, Khadiza, Nguyen, Vien, De La Cruz, Daniel L., Prokai, Laszlo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466286/ https://www.ncbi.nlm.nih.gov/pubmed/34575465 http://dx.doi.org/10.3390/pharmaceutics13091392

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