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Intraoperative Lung Ultrasound (ILU) for the Assessment of Pulmonary Nodules

Background: The primary aim of this study was to confirm the validity of intraoperative lung ultrasound (ILU) as a safe and effective method of localization for difficult to visualize pulmonary nodules during Video-Assisted Thoracoscopic Surgery (VATS) and open thoracotomy. The secondary aim was to...

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Autores principales: Taurchini, Marco, Quarato, Carla Maria Irene, Frongillo, Elisabetta Maria, Ferretti, Gian Maria, Cipriani, Cristiana, Bizzarri, Marco, Foschino Barbaro, Maria Pia, Lacedonia, Donato, Simeone, Annalisa, Graziano, Paolo, Dimitri, Lucia, Maiello, Evaristo, Cavaliere, Lucio, De Cosmo, Salvatore, Sperandeo, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466360/
https://www.ncbi.nlm.nih.gov/pubmed/34574032
http://dx.doi.org/10.3390/diagnostics11091691
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author Taurchini, Marco
Quarato, Carla Maria Irene
Frongillo, Elisabetta Maria
Ferretti, Gian Maria
Cipriani, Cristiana
Bizzarri, Marco
Foschino Barbaro, Maria Pia
Lacedonia, Donato
Simeone, Annalisa
Graziano, Paolo
Dimitri, Lucia
Maiello, Evaristo
Cavaliere, Lucio
De Cosmo, Salvatore
Sperandeo, Marco
author_facet Taurchini, Marco
Quarato, Carla Maria Irene
Frongillo, Elisabetta Maria
Ferretti, Gian Maria
Cipriani, Cristiana
Bizzarri, Marco
Foschino Barbaro, Maria Pia
Lacedonia, Donato
Simeone, Annalisa
Graziano, Paolo
Dimitri, Lucia
Maiello, Evaristo
Cavaliere, Lucio
De Cosmo, Salvatore
Sperandeo, Marco
author_sort Taurchini, Marco
collection PubMed
description Background: The primary aim of this study was to confirm the validity of intraoperative lung ultrasound (ILU) as a safe and effective method of localization for difficult to visualize pulmonary nodules during Video-Assisted Thoracoscopic Surgery (VATS) and open thoracotomy. The secondary aim was to enhance knowledge on the morphological patterns of presentation of pulmonary nodules on direct ultrasound examination. Materials and methods: 131 patients with lung nodule and indication for surgery were enrolled. All patients underwent pre-operative imaging of the chest, including Chest Computed Tomography (CT) and Transthoracic Ultrasound (TUS), and surgical procedures for histological assessment of pulmonary nodules (VATS or open thoracotomy). Results: The identification of 100.00% of lung nodules was allowed by ILU, while the detection rate of digital palpation was 94.66%. It was not possible to associate any specific ILU echostructural pattern to both benign or malignant lesions. However, the actual histological margins of the lesions in the operating samples were corresponding to those visualized at ILU in 125/131 (95.42%) cases. No complications have been reported with ILU employment. Conclusions: In our experience, ILU performed during both open surgery and VATS demonstrated to be a reliable and safe method for visualization and localization of pulmonary nodules non previously assessed on digital palpation. In addition, ILU showed to allow a clear nodule’s margins’ definition matching, in most cases, with the actual histological margins.
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spelling pubmed-84663602021-09-27 Intraoperative Lung Ultrasound (ILU) for the Assessment of Pulmonary Nodules Taurchini, Marco Quarato, Carla Maria Irene Frongillo, Elisabetta Maria Ferretti, Gian Maria Cipriani, Cristiana Bizzarri, Marco Foschino Barbaro, Maria Pia Lacedonia, Donato Simeone, Annalisa Graziano, Paolo Dimitri, Lucia Maiello, Evaristo Cavaliere, Lucio De Cosmo, Salvatore Sperandeo, Marco Diagnostics (Basel) Article Background: The primary aim of this study was to confirm the validity of intraoperative lung ultrasound (ILU) as a safe and effective method of localization for difficult to visualize pulmonary nodules during Video-Assisted Thoracoscopic Surgery (VATS) and open thoracotomy. The secondary aim was to enhance knowledge on the morphological patterns of presentation of pulmonary nodules on direct ultrasound examination. Materials and methods: 131 patients with lung nodule and indication for surgery were enrolled. All patients underwent pre-operative imaging of the chest, including Chest Computed Tomography (CT) and Transthoracic Ultrasound (TUS), and surgical procedures for histological assessment of pulmonary nodules (VATS or open thoracotomy). Results: The identification of 100.00% of lung nodules was allowed by ILU, while the detection rate of digital palpation was 94.66%. It was not possible to associate any specific ILU echostructural pattern to both benign or malignant lesions. However, the actual histological margins of the lesions in the operating samples were corresponding to those visualized at ILU in 125/131 (95.42%) cases. No complications have been reported with ILU employment. Conclusions: In our experience, ILU performed during both open surgery and VATS demonstrated to be a reliable and safe method for visualization and localization of pulmonary nodules non previously assessed on digital palpation. In addition, ILU showed to allow a clear nodule’s margins’ definition matching, in most cases, with the actual histological margins. MDPI 2021-09-16 /pmc/articles/PMC8466360/ /pubmed/34574032 http://dx.doi.org/10.3390/diagnostics11091691 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Taurchini, Marco
Quarato, Carla Maria Irene
Frongillo, Elisabetta Maria
Ferretti, Gian Maria
Cipriani, Cristiana
Bizzarri, Marco
Foschino Barbaro, Maria Pia
Lacedonia, Donato
Simeone, Annalisa
Graziano, Paolo
Dimitri, Lucia
Maiello, Evaristo
Cavaliere, Lucio
De Cosmo, Salvatore
Sperandeo, Marco
Intraoperative Lung Ultrasound (ILU) for the Assessment of Pulmonary Nodules
title Intraoperative Lung Ultrasound (ILU) for the Assessment of Pulmonary Nodules
title_full Intraoperative Lung Ultrasound (ILU) for the Assessment of Pulmonary Nodules
title_fullStr Intraoperative Lung Ultrasound (ILU) for the Assessment of Pulmonary Nodules
title_full_unstemmed Intraoperative Lung Ultrasound (ILU) for the Assessment of Pulmonary Nodules
title_short Intraoperative Lung Ultrasound (ILU) for the Assessment of Pulmonary Nodules
title_sort intraoperative lung ultrasound (ilu) for the assessment of pulmonary nodules
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466360/
https://www.ncbi.nlm.nih.gov/pubmed/34574032
http://dx.doi.org/10.3390/diagnostics11091691
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