Cathepsin S Evokes PAR(2)-Dependent Pain in Oral Squamous Cell Carcinoma Patients and Preclinical Mouse Models

SIMPLE SUMMARY: Oral cancer is often deadly and severely painful. Because this form of cancer pain cannot be adequately treated with current medications including opiates, new treatment approaches are needed. Cathepsin S, a lysosomal cysteine protease may play a role in oral cancer pain through a pr...

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Detalles Bibliográficos
Autores principales: Tu, Nguyen Huu, Inoue, Kenji, Chen, Elyssa, Anderson, Bethany M., Sawicki, Caroline M., Scheff, Nicole N., Tran, Hung D., Kim, Dong H., Alemu, Robel G., Yang, Lei, Dolan, John C., Liu, Cheng Z., Janal, Malvin N., Latorre, Rocco, Jensen, Dane D., Bunnett, Nigel W., Edgington-Mitchell, Laura E., Schmidt, Brian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466361/
https://www.ncbi.nlm.nih.gov/pubmed/34572924
http://dx.doi.org/10.3390/cancers13184697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466361/
https://www.ncbi.nlm.nih.gov/pubmed/34572924
http://dx.doi.org/10.3390/cancers13184697

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