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A Simple Synthesis Route for Selectively Methylated β-Cyclodextrin Using a Copper Complex Sandwich Protecting Strategy
This communication reports a novel synthesis route for the preparation of monofunctionalized β-cyclodextrin in a single stage. The approach involves only the in-situ protection of secondary hydroxyl groups as an excellent alternative to the classical procedure involving a series of five steps of pro...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466452/ https://www.ncbi.nlm.nih.gov/pubmed/34577140 http://dx.doi.org/10.3390/molecules26185669 |
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author | Bucur, Stefan Niculaua, Marius Ciobanu, Catalina Ionica Lungu, Neculai Catalin Mangalagiu, Ionel |
author_facet | Bucur, Stefan Niculaua, Marius Ciobanu, Catalina Ionica Lungu, Neculai Catalin Mangalagiu, Ionel |
author_sort | Bucur, Stefan |
collection | PubMed |
description | This communication reports a novel synthesis route for the preparation of monofunctionalized β-cyclodextrin in a single stage. The approach involves only the in-situ protection of secondary hydroxyl groups as an excellent alternative to the classical procedure involving a series of five steps of protection and deprotection of hydroxyl groups (both primary and secondary ones) belonging to β-cyclodextrin. |
format | Online Article Text |
id | pubmed-8466452 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-84664522021-09-27 A Simple Synthesis Route for Selectively Methylated β-Cyclodextrin Using a Copper Complex Sandwich Protecting Strategy Bucur, Stefan Niculaua, Marius Ciobanu, Catalina Ionica Lungu, Neculai Catalin Mangalagiu, Ionel Molecules Communication This communication reports a novel synthesis route for the preparation of monofunctionalized β-cyclodextrin in a single stage. The approach involves only the in-situ protection of secondary hydroxyl groups as an excellent alternative to the classical procedure involving a series of five steps of protection and deprotection of hydroxyl groups (both primary and secondary ones) belonging to β-cyclodextrin. MDPI 2021-09-18 /pmc/articles/PMC8466452/ /pubmed/34577140 http://dx.doi.org/10.3390/molecules26185669 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Communication Bucur, Stefan Niculaua, Marius Ciobanu, Catalina Ionica Lungu, Neculai Catalin Mangalagiu, Ionel A Simple Synthesis Route for Selectively Methylated β-Cyclodextrin Using a Copper Complex Sandwich Protecting Strategy |
title | A Simple Synthesis Route for Selectively Methylated β-Cyclodextrin Using a Copper Complex Sandwich Protecting Strategy |
title_full | A Simple Synthesis Route for Selectively Methylated β-Cyclodextrin Using a Copper Complex Sandwich Protecting Strategy |
title_fullStr | A Simple Synthesis Route for Selectively Methylated β-Cyclodextrin Using a Copper Complex Sandwich Protecting Strategy |
title_full_unstemmed | A Simple Synthesis Route for Selectively Methylated β-Cyclodextrin Using a Copper Complex Sandwich Protecting Strategy |
title_short | A Simple Synthesis Route for Selectively Methylated β-Cyclodextrin Using a Copper Complex Sandwich Protecting Strategy |
title_sort | simple synthesis route for selectively methylated β-cyclodextrin using a copper complex sandwich protecting strategy |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466452/ https://www.ncbi.nlm.nih.gov/pubmed/34577140 http://dx.doi.org/10.3390/molecules26185669 |
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