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A Simple Synthesis Route for Selectively Methylated β-Cyclodextrin Using a Copper Complex Sandwich Protecting Strategy

This communication reports a novel synthesis route for the preparation of monofunctionalized β-cyclodextrin in a single stage. The approach involves only the in-situ protection of secondary hydroxyl groups as an excellent alternative to the classical procedure involving a series of five steps of pro...

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Detalles Bibliográficos
Autores principales: Bucur, Stefan, Niculaua, Marius, Ciobanu, Catalina Ionica, Lungu, Neculai Catalin, Mangalagiu, Ionel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466452/
https://www.ncbi.nlm.nih.gov/pubmed/34577140
http://dx.doi.org/10.3390/molecules26185669
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author Bucur, Stefan
Niculaua, Marius
Ciobanu, Catalina Ionica
Lungu, Neculai Catalin
Mangalagiu, Ionel
author_facet Bucur, Stefan
Niculaua, Marius
Ciobanu, Catalina Ionica
Lungu, Neculai Catalin
Mangalagiu, Ionel
author_sort Bucur, Stefan
collection PubMed
description This communication reports a novel synthesis route for the preparation of monofunctionalized β-cyclodextrin in a single stage. The approach involves only the in-situ protection of secondary hydroxyl groups as an excellent alternative to the classical procedure involving a series of five steps of protection and deprotection of hydroxyl groups (both primary and secondary ones) belonging to β-cyclodextrin.
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spelling pubmed-84664522021-09-27 A Simple Synthesis Route for Selectively Methylated β-Cyclodextrin Using a Copper Complex Sandwich Protecting Strategy Bucur, Stefan Niculaua, Marius Ciobanu, Catalina Ionica Lungu, Neculai Catalin Mangalagiu, Ionel Molecules Communication This communication reports a novel synthesis route for the preparation of monofunctionalized β-cyclodextrin in a single stage. The approach involves only the in-situ protection of secondary hydroxyl groups as an excellent alternative to the classical procedure involving a series of five steps of protection and deprotection of hydroxyl groups (both primary and secondary ones) belonging to β-cyclodextrin. MDPI 2021-09-18 /pmc/articles/PMC8466452/ /pubmed/34577140 http://dx.doi.org/10.3390/molecules26185669 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Bucur, Stefan
Niculaua, Marius
Ciobanu, Catalina Ionica
Lungu, Neculai Catalin
Mangalagiu, Ionel
A Simple Synthesis Route for Selectively Methylated β-Cyclodextrin Using a Copper Complex Sandwich Protecting Strategy
title A Simple Synthesis Route for Selectively Methylated β-Cyclodextrin Using a Copper Complex Sandwich Protecting Strategy
title_full A Simple Synthesis Route for Selectively Methylated β-Cyclodextrin Using a Copper Complex Sandwich Protecting Strategy
title_fullStr A Simple Synthesis Route for Selectively Methylated β-Cyclodextrin Using a Copper Complex Sandwich Protecting Strategy
title_full_unstemmed A Simple Synthesis Route for Selectively Methylated β-Cyclodextrin Using a Copper Complex Sandwich Protecting Strategy
title_short A Simple Synthesis Route for Selectively Methylated β-Cyclodextrin Using a Copper Complex Sandwich Protecting Strategy
title_sort simple synthesis route for selectively methylated β-cyclodextrin using a copper complex sandwich protecting strategy
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466452/
https://www.ncbi.nlm.nih.gov/pubmed/34577140
http://dx.doi.org/10.3390/molecules26185669
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