Maternal High-Fat Diet Promotes Abdominal Aortic Aneurysm Expansion in Adult Offspring by Epigenetic Regulation of IRF8-Mediated Osteoclast-like Macrophage Differentiation

Maternal high-fat diet (HFD) modulates vascular remodeling in adult offspring. Here, we investigated the impact of maternal HFD on abdominal aortic aneurysm (AAA) development. Female wild-type mice were fed an HFD or normal diet (ND). AAA was induced in eight-week-old pups using calcium chloride. Ma...

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Detalles Bibliográficos
Autores principales: Saburi, Makoto, Yamada, Hiroyuki, Wada, Naotoshi, Motoyama, Shinichiro, Sugimoto, Takeshi, Kubota, Hiroshi, Miyawaki, Daisuke, Wakana, Noriyuki, Kami, Daisuke, Ogata, Takehiro, Matoba, Satoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466477/
https://www.ncbi.nlm.nih.gov/pubmed/34571873
http://dx.doi.org/10.3390/cells10092224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466477/
https://www.ncbi.nlm.nih.gov/pubmed/34571873
http://dx.doi.org/10.3390/cells10092224

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