Cargando…

Transcriptomic Response Dynamics of Human Primary and Immortalized Adrenocortical Cells to Steroidogenic Stimuli

Adrenal steroid hormone production is a dynamic process stimulated by adrenocorticotropic hormone (ACTH) and angiotensin II (AngII). These ligands initialize a rapid and robust gene expression response required for steroidogenesis. Here, we compare the predominant human immortalized cell line model,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wellman, Kimberly, Fu, Rui, Baldwin, Amber, Rege, Juilee, Murphy, Elisabeth, Rainey, William E., Mukherjee, Neelanjan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466536/ https://www.ncbi.nlm.nih.gov/pubmed/34572026 http://dx.doi.org/10.3390/cells10092376

Ejemplares similares

RNA-binding proteins regulate aldosterone homeostasis in human steroidogenic cells
por: Fu, Rui, et al.
Publicado: (2021)

RNA Decay Controls the Kinetics of the Angiotensin II Gene Expression Response
por: Wellman, Kimberly, et al.
Publicado: (2021)

SAT-LB34 Repressive Epigenetic Programs Reinforce Steroidogenic Differentiation and Wnt/β-Catenin Signaling in Aggressive Adrenocortical Carcinoma
por: Mohan, Dipika R, et al.
Publicado: (2020)

Incomplete Pattern of Steroidogenic Protein Expression in Functioning Adrenocortical Carcinomas
por: Pereira, Sofia S., et al.
Publicado: (2020)

Steroidogenic enzyme profile in an androgen-secreting adrenocortical oncocytoma associated with hirsustism
por: Tetsi Nomigni, Milène, et al.
Publicado: (2015)

Steroidogenic enzyme profile in an androgen-secreting adrenocortical oncocytoma associated with hirsustism
por: Nomigni, Milène Tetsi, et al.
Publicado: (2015)

OR26-5 Musashi-2 Regulatory Interactions Promote Adrenal Steroidogenesis
por: Baldwin, Amber, et al.
Publicado: (2022)

ULTRASTRUCTURE, STEROIDOGENIC POTENTIAL, AND ENERGY METABOLISM OF THE SNELL ADRENOCORTICAL CARCINOMA 494 : A Comparison with Normal Adrenocortical Tissue
por: Kimmel, G. L., et al.
Publicado: (1974)

SUN-044 Methylation Status and Gene Expression of Steroidogenic Enzymes in Benign Adrenocortical Tumors
por: Di Dalmazi, Guido, et al.
Publicado: (2019)

Steroidogenic Factor 1, a Goldilocks Transcription Factor from Adrenocortical Organogenesis to Malignancy
por: Relav, Lauriane, et al.
Publicado: (2023)

OR08-02 In Situ Reconstruction Of Distinct Normal And Pathological Cell Populations Within The Human Adrenal Gland Using Spatial Transcriptomics
por: Rui, Fu, et al.
Publicado: (2023)

SAT-LB063 The ZFP36 Family of RNA-Binding Proteins Regulate Human Steroidogenesis
por: Wellman, Kimberly, et al.
Publicado: (2019)

Steroidogenic Acute Regulatory Protein Overexpression Correlates with Protein Kinase A Activation in Adrenocortical Adenoma
por: Zhou, Weiwei, et al.
Publicado: (2016)

A Comprehensive Investigation of Steroidogenic Signaling in Classical and New Experimental Cell Models of Adrenocortical Carcinoma
por: Sigala, Sandra, et al.
Publicado: (2022)

RNA-Binding Protein Musashi-2 Inhibits Aldosterone Production
por: Bartholomay, Kathryn, et al.
Publicado: (2021)

A Case of Metastatic Adrenocortical Carcinoma Diagnosed with Steroidogenic Factor-1 in a Sprague-Dawley Rat
por: Takai, Yuichi, et al.
Publicado: (2013)

SAT-010 Adrenal Androgen Synthesis in Aging Men
por: Namba, Aya, et al.
Publicado: (2019)

OR29-3 Targeted Assessment of G0S2 Methylation Identifies a Rapidly Recurrent, Routinely Fatal Molecular Subtype of Adrenocortical Carcinoma
por: Mohan, Dipika, et al.
Publicado: (2019)

Development of Human Adrenocortical Adenoma (HAA1) Cell Line from Zona Reticularis
por: Ghayee, Hans K., et al.
Publicado: (2022)

SUN-LB23 Translational Feasibility of Steroidogenic Factor-1 Antagonists as a Novel Targeted Therapy for Adrenocortical Cancer
por: Crowe, Paul D, et al.
Publicado: (2020)

SAT-345 11-oxygenated Adrenal Androgens Are Produced In Several Mammalian Species
por: Rege, Juilee, et al.
Publicado: (2019)

RF21 | PSAT76 Epigenetic Programs Stabilize a Differentiated Cell State Required for Sustained Proliferation in Adrenocortical Carcinoma
por: Mohan, Dipika, et al.
Publicado: (2022)

SAT-LB90 Angiotensin II and ACTH Receptor Expression in Aldosterone-Producing Adenomas
por: Lim, Jung Soo, et al.
Publicado: (2020)

OR13-5 Bone Morphogenetic Protein-4 (BMP4) Inhibits Adrenal Cell Cortisol Synthesis by Blocking CYP17A1 and CYP11B1 Expression.
por: Garber, Scott, et al.
Publicado: (2022)

SAT267 BMP4, GDF11 And TGFβ2 Repress Adrenal Cell Cortisol Production By Blocking CYP17A1 And CYP11B1 Expression
por: Fischbach, Emily Catherine, et al.
Publicado: (2023)

An immortalized steroidogenic goat granulosa cell line as a model system to study the effect of the endoplasmic reticulum (ER)-stress response on steroidogenesis
por: YANG, Diqi, et al.
Publicado: (2016)

Aldosterone-Regulating Receptors and Aldosterone-Driver Somatic Mutations
por: Lim, Jung Soo, et al.
Publicado: (2021)

Differential Response of Transcription Factors to Activated Kinases in Steroidogenic and Non-Steroidogenic Cells †
por: Pierre, Kenley Joule, et al.
Publicado: (2022)

Androstenedione changes steroidogenic activity of SGBS cells
por: Ernst, Jana, et al.
Publicado: (2020)

Steroidogenic effects of Taraxacum officinale extract on the levels of steroidogenic enzymes in mouse Leydig cells
por: Chung, Hyun Joo, et al.
Publicado: (2018)

Human Adrenal Cortical Zone Changes With Aging
por: Tezuka, Yuta, et al.
Publicado: (2021)

PSAT073 The Human Gonads Do Not Contribute to the Circulating Pool of 11-Oxygenated Androgens
por: Rabbah, Amira, et al.
Publicado: (2022)

Expression of steroidogenic enzymes and metabolism of steroids in COS-7 cells known as non-steroidogenic cells
por: Nozaki, Mitsuki, et al.
Publicado: (2018)

Dynamic Changes in the Follicular Transcriptome and Promoter DNA Methylation Pattern of Steroidogenic Genes in Chicken Follicles throughout the Ovulation Cycle
por: Zhu, Guiyu, et al.
Publicado: (2015)

Establishment of an immortalized human endometrial stromal cell line with functional responses to ovarian stimuli
por: Yuhki, Munehiro, et al.
Publicado: (2011)

FRI192 Serum Steroid Biomarkers For The Differential Diagnosis Of Adrenocortical Carcinoma (ACC) And Adrenocortical Adenoma (ACA)
por: van Rooyen, Desmaré, et al.
Publicado: (2023)

Correction: Sigala et al. A Comprehensive Investigation of Steroidogenic Signaling in Classical and New Experimental Cell Models of Adrenocortical Carcinoma. Cells 2022, 11, 1439
por: Sigala, Sandra, et al.
Publicado: (2023)

SUN-387 ACTH-Independent Cushing Syndrome from Pregnancy-Induced Micronodular Hyperplasia
por: Affinati, Alison, et al.
Publicado: (2019)

Small-molecule Ro-08-2750 interacts with many RNA-binding proteins and elicits MUSASHI2-independent phenotypes
por: Walters, Kathryn, et al.
Publicado: (2023)

Elevated fetal steroidogenic activity in autism
por: Baron-Cohen, S, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_j04tg40e7uph3j1bvps5k04qqc