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Tissue of Origin, but Not XCI State, Influences Germ Cell Differentiation from Human Pluripotent Stem Cells

Human pluripotent stem cells (hPSCs) are not only a promising tool to investigate differentiation to many cell types, including the germline, but are also a potential source of cells to use for regenerative medicine purposes in the future. However, current in vitro models to generate human primordia...

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Detalles Bibliográficos
Autores principales: Chang, Yolanda W., Overeem, Arend W., Roelse, Celine M., Fan, Xueying, Freund, Christian, Chuva de Sousa Lopes, Susana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466594/
https://www.ncbi.nlm.nih.gov/pubmed/34572048
http://dx.doi.org/10.3390/cells10092400

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