Cargando…

Metabolomics Signature of Plasma Renin Activity and Linkage with Blood Pressure Response to Beta Blockers and Thiazide Diuretics in Hypertensive European American Patients

Plasma renin activity (PRA) is a predictive biomarker of blood pressure (BP) response to antihypertensives in European–American hypertensive patients. We aimed to identify the metabolic signatures of baseline PRA and the linkages with BP response to β-blockers and thiazides. Using data from the Phar...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mehanna, Mai, McDonough, Caitrin W., Smith, Steven M., Gong, Yan, Gums, John G., Chapman, Arlene B., Johnson, Julie A., McIntyre, Lauren, Cooper-DeHoff, Rhonda M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466669/ https://www.ncbi.nlm.nih.gov/pubmed/34564461 http://dx.doi.org/10.3390/metabo11090645

Ejemplares similares

Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response
por: Singh, Sonal, et al.
Publicado: (2019)

Whole Transcriptome Sequencing Analyses Reveal Molecular Markers of Blood Pressure Response to Thiazide Diuretics
por: Sá, Ana Caroline C., et al.
Publicado: (2017)

Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β‐Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil‐SR Trandolapril Study) Trials
por: Magvanjav, Oyunbileg, et al.
Publicado: (2017)

Blood pressure signature genes and blood pressure response to thiazide diuretics: results from the PEAR and PEAR-2 studies
por: Sá, Ana Caroline C., et al.
Publicado: (2018)

Influence of Genetic West African Ancestry on Metabolomics among Hypertensive Patients
por: Mehanna, Mai, et al.
Publicado: (2022)

Sphingolipid Metabolic Pathway Impacts Thiazide Diuretics Blood Pressure Response: Insights From Genomics, Metabolomics, and Lipidomics
por: Shahin, Mohamed H., et al.
Publicado: (2017)

Genomic Association Analysis Reveals Variants Associated With Blood Pressure Response to Beta‐Blockers in European Americans
por: Singh, Sonal, et al.
Publicado: (2019)

Thiazide and thiazide-like diuretics in nephrolithiasis
por: Cunha, Tamara da Silva, et al.
Publicado: (2020)

Comparison of thiazide‐like diuretics versus thiazide‐type diuretics: a meta‐analysis
por: Liang, Wenjing, et al.
Publicado: (2017)

2246: Characterization of resistant hypertension in a statewide electronic health record-based database (OneFlorida)
por: McDonough, Caitrin W., et al.
Publicado: (2018)

Impact of Angiotensin Receptor Blockers, Beta Blockers, Calcium Channel Blockers and Thiazide Diuretics on Survival of Ovarian Cancer Patients
por: Cho, Min Ae, et al.
Publicado: (2020)

Optimizing Antihypertensive Medication Classification in Electronic Health Record-Based Data: Classification System Development and Methodological Comparison
por: McDonough, Caitrin W, et al.
Publicado: (2020)

Hyperuricemia Associated with Thiazide Diuretics in Hypertensive Adults
por: Raja, Ravi, et al.
Publicado: (2019)

Thiazide diuretics are back in CKD: the case of chlorthalidone
por: Minutolo, Roberto, et al.
Publicado: (2022)

Redefining diuretics use in hypertension: why select a thiazide-like diuretic?
por: Burnier, Michel, et al.
Publicado: (2019)

Rationale for triple fixed-dose combination therapy with an angiotensin II receptor blocker, a calcium channel blocker, and a thiazide diuretic
por: Volpe, Massimo, et al.
Publicado: (2012)

Maximising antihypertensive effects of angiotensin II receptor blockers with thiazide diuretic combination therapy: focus on irbesartan/hydrochlorothiazide
por: Flack, J M
Publicado: (2007)

Large‐Scale Gene‐Centric Analysis Identifies Polymorphisms for Resistant Hypertension
por: Fontana, Vanessa, et al.
Publicado: (2014)

Duloxetine-induced hyponatremia in an elderly patient treated with thiazide diuretics
por: Mori, Miyu, et al.
Publicado: (2014)

Mechanism of Thiazide Diuretic Arterial Pressure Reduction: The Search Continues
por: Rapoport, Robert M., et al.
Publicado: (2019)

Association between thiazide diuretics and skin cancer: still nebulous
por: Parmar, Malvinder S.
Publicado: (2021)

Pairwise comparison of hydrochlorothiazide and chlorthalidone responses among hypertensive patients
por: Chekka, Lakshmi Manasa S., et al.
Publicado: (2022)

Effectiveness of thiazide and thiazide-like diuretics in advanced chronic kidney disease: a systematic review and meta-analysis
por: Teles, Flávio, et al.
Publicado: (2023)

Genome‐Wide Association Approach Identified Novel Genetic Predictors of Heart Rate Response to β‐Blockers
por: Shahin, Mohamed H., et al.
Publicado: (2018)

Hypokalaemic paralysis secondary to thiazide diuretic abuse: an unexpected outcome for cauda equina syndrome
por: Cawley, Derek T., et al.
Publicado: (2011)

Case report: a thiazide diuretic to treat polyuria induced by tolvaptan
por: Kramers, Bart J., et al.
Publicado: (2018)

Association between newly initiated thiazide diuretics and hospitalization due to hyponatremia
por: Mannheimer, Buster, et al.
Publicado: (2021)

Adding thiazide to a renin–angiotensin blocker improves left ventricular relaxation and improves heart failure in patients with hypertension
por: Ito, Hiroshi, et al.
Publicado: (2012)

Genome Wide Association Study Identifies the HMGCS2 Locus to be Associated With Chlorthalidone Induced Glucose Increase in Hypertensive Patients
por: Singh, Sonal, et al.
Publicado: (2018)

Genome‐Wide Meta‐Analysis of Blood Pressure Response to β(1)‐Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies)
por: Singh, Sonal, et al.
Publicado: (2019)

Back to thiazide-diuretics for hypertension: reflections after a decade of irrational prescribing
por: Fretheim, Atle
Publicado: (2003)

Evaluation of thiazide diuretic use as preferred therapy in uncomplicated essential hypertension patients
por: Greene, Ronald S., et al.
Publicado: (2007)

Efficacy of ingenol mebutate gel for actinic keratosis in patients treated by thiazide diuretics
por: Campione, Elena, et al.
Publicado: (2016)

The non-diuretic hypotensive effects of thiazides are enhanced during volume depletion states
por: Alshahrani, Saeed, et al.
Publicado: (2017)

Kidney stones and thiazide diuretics: revisiting old assumptions in light of the NOSTONE trial
por: Cirillo, Luigi, et al.
Publicado: (2023)

Thiazide Diuretic Dose and Risk of Kidney Stones in Older Adults: A Retrospective Cohort Study
por: Alexander, R. Todd, et al.
Publicado: (2018)

Melatonin Pathway and Atenolol‐Related Glucose Dysregulation: Is There a Correlation?
por: Chang, SW, et al.
Publicado: (2016)

Attenuated renal excretion in response to thiazide diuretics in Gitelman's syndrome: a case report.
por: Yeum, Chung-Ho, et al.
Publicado: (2002)

Proton-pump Inhibitor-induced Severe Hypomagnesemia and Hypocalcemia are Clinically Masked by Thiazide Diuretic
por: Uehara, Atsuko, et al.
Publicado: (2019)

Interamerican Society of Cardiology (IASC) position statement: Chlorthalidone vs. thiazide-type diuretics()
por: Pareek, Anil, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_dkkunjcupmum5am5pt4vjb7hvp