Rutaecarpine Increases Anticancer Drug Sensitivity in Drug-Resistant Cells through MARCH8-Dependent ABCB1 Degradation

The overexpression of adenosine triphosphate (ATP)-binding cassette (ABC) subfamily B member 1 (ABCB1; P-glycoprotein; MDR1) in some types of cancer cells is one of the mechanisms responsible for the development of multidrug resistance (MDR), which leads to the failure of chemotherapy. Therefore, it...

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Detalles Bibliográficos
Autores principales: Zou, Tingting, Zeng, Cheng, Qu, Junyan, Yan, Xiaohua, Lin, Zhenghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466742/
https://www.ncbi.nlm.nih.gov/pubmed/34572328
http://dx.doi.org/10.3390/biomedicines9091143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466742/
https://www.ncbi.nlm.nih.gov/pubmed/34572328
http://dx.doi.org/10.3390/biomedicines9091143

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