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EUS-Guided Biopsy with a Novel Puncture Biopsy Forceps Needle—Feasibility Study
Endoscopic ultrasound (EUS) with fine needle aspiration (FNA) or biopsy (FNB) to diagnose lesions in the gastrointestinal tract is common. Demand for histology sampling to identify treatment-specific targets is increasing. Various core biopsy FNB needles to obtain tissue for histology are currently...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466864/ https://www.ncbi.nlm.nih.gov/pubmed/34573978 http://dx.doi.org/10.3390/diagnostics11091638 |
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author | Litjens, Geke Gerges, Christian Shastri, Yogesh M. Somani, Piyush Beyna, Torsten Neuhaus, Horst van Laarhoven, Cornelis J. H. M. Prokop, Mathias Siersema, Peter D. Hermans, John J. van Geenen, Erwin J. M. |
author_facet | Litjens, Geke Gerges, Christian Shastri, Yogesh M. Somani, Piyush Beyna, Torsten Neuhaus, Horst van Laarhoven, Cornelis J. H. M. Prokop, Mathias Siersema, Peter D. Hermans, John J. van Geenen, Erwin J. M. |
author_sort | Litjens, Geke |
collection | PubMed |
description | Endoscopic ultrasound (EUS) with fine needle aspiration (FNA) or biopsy (FNB) to diagnose lesions in the gastrointestinal tract is common. Demand for histology sampling to identify treatment-specific targets is increasing. Various core biopsy FNB needles to obtain tissue for histology are currently available, however, with variable (37–97%) histology yields. In this multicenter study, we evaluated performance, safety, and user experience of a novel device (the puncture biopsy forceps (PBF) needle). Twenty-four procedures with the PBF needle were performed in 24 patients with a suspected pancreatic lesion (n = 10), subepithelial lesion (n = 10), lymph node (n = 3), or pararectal mass (n = 1). In 20/24 (83%) procedures, the PBF needle yielded sufficient material for interpretation (sample adequacy). In 17/24 (71%), a correct diagnosis was made with the material from the PBF needle (diagnostic accuracy). All participating endoscopists experienced a learning curve. (Per)procedural technical issues occurred in four cases (17%), but there were no adverse events. The PBF needle is a safe and potentially useful device to obtain an EUS-guided biopsy specimen. As the design of the PBF needle is different to core biopsy FNB needles, specific training will likely further improve the performance of the PBF needle. Furthermore, the design of the needle needs further improvement to make it more robust in clinical practice. |
format | Online Article Text |
id | pubmed-8466864 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-84668642021-09-27 EUS-Guided Biopsy with a Novel Puncture Biopsy Forceps Needle—Feasibility Study Litjens, Geke Gerges, Christian Shastri, Yogesh M. Somani, Piyush Beyna, Torsten Neuhaus, Horst van Laarhoven, Cornelis J. H. M. Prokop, Mathias Siersema, Peter D. Hermans, John J. van Geenen, Erwin J. M. Diagnostics (Basel) Article Endoscopic ultrasound (EUS) with fine needle aspiration (FNA) or biopsy (FNB) to diagnose lesions in the gastrointestinal tract is common. Demand for histology sampling to identify treatment-specific targets is increasing. Various core biopsy FNB needles to obtain tissue for histology are currently available, however, with variable (37–97%) histology yields. In this multicenter study, we evaluated performance, safety, and user experience of a novel device (the puncture biopsy forceps (PBF) needle). Twenty-four procedures with the PBF needle were performed in 24 patients with a suspected pancreatic lesion (n = 10), subepithelial lesion (n = 10), lymph node (n = 3), or pararectal mass (n = 1). In 20/24 (83%) procedures, the PBF needle yielded sufficient material for interpretation (sample adequacy). In 17/24 (71%), a correct diagnosis was made with the material from the PBF needle (diagnostic accuracy). All participating endoscopists experienced a learning curve. (Per)procedural technical issues occurred in four cases (17%), but there were no adverse events. The PBF needle is a safe and potentially useful device to obtain an EUS-guided biopsy specimen. As the design of the PBF needle is different to core biopsy FNB needles, specific training will likely further improve the performance of the PBF needle. Furthermore, the design of the needle needs further improvement to make it more robust in clinical practice. MDPI 2021-09-07 /pmc/articles/PMC8466864/ /pubmed/34573978 http://dx.doi.org/10.3390/diagnostics11091638 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Litjens, Geke Gerges, Christian Shastri, Yogesh M. Somani, Piyush Beyna, Torsten Neuhaus, Horst van Laarhoven, Cornelis J. H. M. Prokop, Mathias Siersema, Peter D. Hermans, John J. van Geenen, Erwin J. M. EUS-Guided Biopsy with a Novel Puncture Biopsy Forceps Needle—Feasibility Study |
title | EUS-Guided Biopsy with a Novel Puncture Biopsy Forceps Needle—Feasibility Study |
title_full | EUS-Guided Biopsy with a Novel Puncture Biopsy Forceps Needle—Feasibility Study |
title_fullStr | EUS-Guided Biopsy with a Novel Puncture Biopsy Forceps Needle—Feasibility Study |
title_full_unstemmed | EUS-Guided Biopsy with a Novel Puncture Biopsy Forceps Needle—Feasibility Study |
title_short | EUS-Guided Biopsy with a Novel Puncture Biopsy Forceps Needle—Feasibility Study |
title_sort | eus-guided biopsy with a novel puncture biopsy forceps needle—feasibility study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466864/ https://www.ncbi.nlm.nih.gov/pubmed/34573978 http://dx.doi.org/10.3390/diagnostics11091638 |
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