Cargando…
Synaptic Alterations in a Transgenic Model of Tuberous Sclerosis Complex: Relevance to Autism Spectrum Disorders
Tuberous sclerosis complex (TSC) is a rare, multi-system genetic disease with serious neurological and mental symptoms, including autism. Mutations in the TSC1/TSC2 genes lead to the overactivation of mTOR signalling, which is also linked to nonsyndromic autism. Our aim was to analyse synaptic patho...
Autores principales: | Czapski, Grzegorz A., Babiec, Lidia, Jęśko, Henryk, Gąssowska-Dobrowolska, Magdalena, Cieślik, Magdalena, Matuszewska, Marta, Frontczak-Baniewicz, Małgorzata, Zajdel, Karolina, Adamczyk, Agata |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466868/ https://www.ncbi.nlm.nih.gov/pubmed/34576223 http://dx.doi.org/10.3390/ijms221810058 |
Ejemplares similares
-
Microtubule Cytoskeletal Network Alterations in a Transgenic Model of Tuberous Sclerosis Complex: Relevance to Autism Spectrum Disorders
por: Gąssowska-Dobrowolska, Magdalena, et al.
Publicado: (2023) -
Prenatal Exposure to Valproic Acid Affects Microglia and Synaptic Ultrastructure in a Brain-Region-Specific Manner in Young-Adult Male Rats: Relevance to Autism Spectrum Disorders
por: Gąssowska-Dobrowolska, Magdalena, et al.
Publicado: (2020) -
The Synaptic Dysregulation in Adolescent Rats Exposed to Maternal Immune Activation
por: Cieślik, Magdalena, et al.
Publicado: (2021) -
Maternal Immune Activation Induces Neuroinflammation and Cortical Synaptic Deficits in the Adolescent Rat Offspring
por: Cieślik, Magdalena, et al.
Publicado: (2020) -
P2X7 Receptor is Involved in Mitochondrial Dysfunction Induced by Extracellular Alpha Synuclein in Neuroblastoma SH-SY5Y Cells
por: Wilkaniec, Anna, et al.
Publicado: (2020)