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Combined LXR and RXR Agonist Therapy Increases ABCA1 Protein Expression and Enhances ApoAI-Mediated Cholesterol Efflux in Cultured Endothelial Cells

Endothelial ABCA1 expression protects against atherosclerosis and this atheroprotective effect is partially attributed to enhancing apoAI-mediated cholesterol efflux. ABCA1 is a target gene for LXR and RXR; therefore, treating endothelial cells with LXR and/or RXR agonists may increase ABCA1 express...

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Detalles Bibliográficos
Autores principales:	Huang, Kun, Jo, Hanjoong, Echesabal-Chen, Jing, Stamatikos, Alexis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466889/ https://www.ncbi.nlm.nih.gov/pubmed/34564456 http://dx.doi.org/10.3390/metabo11090640

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