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LC-MS/MS Proteomic Study of MCF-7 Cell Treated with Dox and Dox-Loaded Calcium Carbonate Nanoparticles Revealed Changes in Proteins Related to Glycolysis, Actin Signalling, and Energy Metabolism

SIMPLE SUMMARY: This work revealed that DOX-Ar-CC-NPs have the ability to promote cell death in MCF-7 cells, showing high potency in drug delivery. DOX-Ar-CC-NPs prompts cell death of MCF-7 cancer cells in vivo. LC-MS/MS Proteomic experemnt showed alteration on the expression of proteins linked to a...

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Detalles Bibliográficos
Autores principales: Ahmed, Hamidu, Ajat, Mokrish, Mahmood, Rana I., Mansor, Rozaihan, Razak, Intan Shameha Abdul, Al-Obaidi, Jameel R., Razali, Nurhanani, Jaji, Alhaji Zubair, Danmaigoro, Abubakar, Bakar, Md Zuki Abu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466983/
https://www.ncbi.nlm.nih.gov/pubmed/34571787
http://dx.doi.org/10.3390/biology10090909