Cargando…

Characterization and clinical evaluation of microsatellite instability and loss of heterozygosity within tumor-related genes in colorectal cancer

BACKGROUND: Microsatellite instability (MSI) is a biomarker for better outcomes in colorectal cancer (CRC). However, this conclusion is controversial. In addition, MSs can be a useful marker for loss of heterozygosity (LOH) of genes, but this finding has not been well studied. Here, we aimed to clar...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huo, Xueyun, Feng, Dandan, Zhang, Shuangyue, Li, Zhenkun, Li, Xiaohong, Li, Changlong, Guo, Meng, Wang, Jin, Zhang, Zhongtao, Lu, Qingxian, Du, Xiaoyan, Bai, Zhigang, Chen, Zhenwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466986/ https://www.ncbi.nlm.nih.gov/pubmed/34563193 http://dx.doi.org/10.1186/s12920-021-01051-5

Ejemplares similares

Characterization and clinical evaluation of microsatellite instability and loss of heterozygosity in tumor-related genes in gastric cancer
por: Huo, Xueyun, et al.
Publicado: (2021)

Establishment and Characterization of a Newly Established Diabetic Gerbil Line
por: Li, Xiaohong, et al.
Publicado: (2016)

Selection of Genes Associated with Variations in the Circle of Willis in Gerbils Using Suppression Subtractive Hybridization
por: Li, Zhenkun, et al.
Publicado: (2015)

Loss of heterozygosity and microsatellite instability in hepatocellular carcinoma in Taiwan
por: Sheu, J-C, et al.
Publicado: (1999)

Cystatin C Expression is Promoted by VEGFA Blocking, With Inhibitory Effects on Endothelial Cell Angiogenic Functions Including Proliferation, Migration, and Chorioallantoic Membrane Angiogenesis
por: Li, Zhenkun, et al.
Publicado: (2018)

Microsatellite instability and loss of heterozygosity in mammary carcinoma and its probable precursors.
por: Dillon, E. K., et al.
Publicado: (1997)

Genetic instability in lung cancer: concurrent analysis of chromosomal, mini- and microsatellite instability and loss of heterozygosity
por: Ninomiya, H, et al.
Publicado: (2006)

Development of an effective microsatellite marker system to determine the genetic structure of Meriones meridianus populations
por: Liu, Xin, et al.
Publicado: (2020)

Loss of heterozygosity and microsatellite instability as predictive markers among Iranian esophageal cancer patients
por: Forghanifard, Mohammad Mahdi, et al.
Publicado: (2016)

Association of intron microsatellite status and exon mutational profiles of TP53 in human colorectal cancer
por: Liu, Xin, et al.
Publicado: (2019)

Prognostic value of the combination of microsatellite instability and BRAF mutation in colorectal cancer
por: Yang, Yingchi, et al.
Publicado: (2018)

Microsatellite instability and loss of heterozygosity detected in middle-aged patients with sporadic colon cancer: A retrospective study
por: KAMAT, NASIR, et al.
Publicado: (2013)

Chemotherapy induced microsatellite instability and loss of heterozygosity in chromosomes 2, 5, 10, and 17 in solid tumor patients
por: Kamat, Nasir, et al.
Publicado: (2014)

Mlh1 heterozygosity and promoter methylation associates with microsatellite instability in mouse sperm
por: Shrestha, Kul S, et al.
Publicado: (2021)

LncRNA LYPLAL1-DT screening from type 2 diabetes with macrovascular complication contributes protective effects on human umbilical vein endothelial cells via regulating the miR-204-5p/SIRT1 axis
por: Zhu, Xiao, et al.
Publicado: (2022)

High incidence of microsatellite instability and loss of heterozygosity in three loci in breast cancer patients receiving chemotherapy: a prospective study
por: Kamat, Nasir, et al.
Publicado: (2012)

Utility of Circulating Cell-Free DNA in Assessing Microsatellite Instability and Loss of Heterozygosity in Breast Cancer Using Human Identification Approach
por: Al Sharhan, Norah A., et al.
Publicado: (2022)

Development of Microsatellite Marker System to Determine the Genetic Diversity of Experimental Chicken, Duck, Goose, and Pigeon Populations
por: Zhang, Xiulin, et al.
Publicado: (2021)

Loss of heterozygosity and PCR artifacts in a microsatellite analysis of psoriasis and colorectal cancer.
por: Hyun, Jeong Sun, et al.
Publicado: (2002)

Profilin 2 and Endothelial Exosomal Profilin 2 Promote Angiogenesis and Myocardial Infarction Repair in Mice
por: Li, Zhenkun, et al.
Publicado: (2022)

Differential expression of genes identified by suppression subtractive hybridization in liver and adipose tissue of gerbils with diabetes
por: Gong, Jingjing, et al.
Publicado: (2018)

Newly breeding an inbred strain of ischemia-prone Mongolian gerbils and its reproduction and genetic characteristics
por: Du, Xiaoyan, et al.
Publicado: (2017)

PCR-based microsatellite polymorphisms in the detection of loss of heterozygosity in fresh and archival tumour tissue.
por: Gruis, N. A., et al.
Publicado: (1993)

Investigation of Cervical Tumor Biopsies for Chromosomal Loss of Heterozygosity (LOH) and Microsatellite Instability (MSI) at the HLA II Locus in HIV-1/HPV Co-infected Women
por: Chambuso, Ramadhani, et al.
Publicado: (2019)

Loss of heterozygosity at D8S262: an early genetic event of hepatocarcinogenesis
por: Zhu, Qiao, et al.
Publicado: (2015)

Loss of heterozygosity: what is it good for?
por: Ryland, Georgina L., et al.
Publicado: (2015)

Heterozygosity increases microsatellite mutation rate, linking it to demographic history
por: Amos, William, et al.
Publicado: (2008)

Editorial: Microsatellite and microsatellite instability
por: How-Kit, Alexandre, et al.
Publicado: (2023)

Generation of Gene-Knockout Mongolian Gerbils via CRISPR/Cas9 System
por: Wang, Yan, et al.
Publicado: (2020)

Fragile Site Instability in Saccharomyces cerevisiae Causes Loss of Heterozygosity by Mitotic Crossovers and Break-Induced Replication
por: Rosen, Danielle M., et al.
Publicado: (2013)

A new method to detect loss of heterozygosity using cohort heterozygosity comparisons
por: Green, Michael R, et al.
Publicado: (2010)

Sustained Exposure to Helicobacter pylori Lysate Inhibits Apoptosis and Autophagy of Gastric Epithelial Cells
por: He, Yang, et al.
Publicado: (2020)

Establishment of Noninvasive Methods for the Detection of Helicobacter pylori in Mongolian Gerbils and Application of Main Laboratory Gerbil Populations in China
por: Zhang, Xiulin, et al.
Publicado: (2022)

Loss of Heterozygosity and Its Importance in Evolution
por: Smukowski Heil, Caiti
Publicado: (2023)

Implication of Microsatellite Instability in Chinese Cohort of Human Cancers
por: Cui, Meiying, et al.
Publicado: (2020)

MSIsensor-ct: microsatellite instability detection using cfDNA sequencing data
por: Han, Xinyin, et al.
Publicado: (2021)

Dissection of Immune Profiles in Microsatellite Stable and Low Microsatellite Instability Colon Adenocarcinoma by Multiomics Data Analysis
por: Yang, Tao, et al.
Publicado: (2022)

Microsatellite instability in ovarian neoplasms.
por: King, B. L., et al.
Publicado: (1995)

Microsatellite instability in colorectal cancer
por: Horvat, Matej, et al.
Publicado: (2011)

Microsatellite instability in colorectal cancer
por: Nojadeh, Jafar Nouri, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_434lfurv13963a429ki194u3mk