Human pluripotent stem cell-derived cartilaginous organoids promote scaffold-free healing of critical size long bone defects

BACKGROUND: Bones have a remarkable capacity to heal upon fracture. Yet, in large defects or compromised conditions healing processes become impaired, resulting in delayed or non-union. Current therapeutic approaches often utilize autologous or allogeneic bone grafts for bone augmentation. However,...

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Detalles Bibliográficos
Autores principales: Tam, Wai Long, Freitas Mendes, Luís, Chen, Xike, Lesage, Raphaëlle, Van Hoven, Inge, Leysen, Elke, Kerckhofs, Greet, Bosmans, Kathleen, Chai, Yoke Chin, Yamashita, Akihiro, Tsumaki, Noriyuki, Geris, Liesbet, Roberts, Scott J., Luyten, Frank P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466996/
https://www.ncbi.nlm.nih.gov/pubmed/34563248
http://dx.doi.org/10.1186/s13287-021-02580-7

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