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Targeting ErbB3 Receptor in Cancer with Inhibitory Antibodies from Llama
The human ErbB3 receptor confers resistance to the pharmacological inhibition of EGFR and HER2 receptor tyrosine kinases in cancer, which makes it an important therapeutic target. Several anti-ErbB3 monoclonal antibodies that are currently being developed are all classical immunoglobulins. We took a...
Autores principales: | Eliseev, Igor E., Ukrainskaya, Valeria M., Yudenko, Anna N., Mikushina, Anna D., Shmakov, Stanislav V., Afremova, Anastasiya I., Ekimova, Viktoria M., Vronskaia, Anna A., Knyazev, Nickolay A., Shamova, Olga V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467012/ https://www.ncbi.nlm.nih.gov/pubmed/34572289 http://dx.doi.org/10.3390/biomedicines9091106 |
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