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Evaluation of the Pharmacokinetics of Intranasal Drug Delivery for Targeting Cervical Lymph Nodes in Rats
A well-developed lymphatic network is located under the nasal mucosa, and a few drugs that permeate the nasal mucosa are absorbed into the lymphatic capillaries. Lymph from the nasal cavity flows to the cervical lymph nodes (CLNs). In this study, we evaluated the pharmacokinetics of the direct trans...
Autores principales: | Furubayashi, Tomoyuki, Inoue, Daisuke, Kimura, Shunsuke, Tanaka, Akiko, Sakane, Toshiyasu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467065/ https://www.ncbi.nlm.nih.gov/pubmed/34575439 http://dx.doi.org/10.3390/pharmaceutics13091363 |
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