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Enabling Efficient Folding and High-Resolution Crystallographic Analysis of Bracelet Cyclotides
Cyclotides have attracted great interest as drug design scaffolds because of their unique cyclic cystine knotted topology. They are classified into three subfamilies, among which the bracelet subfamily represents the majority and comprises the most bioactive cyclotides, but are the most poorly utili...
Autores principales: | Huang, Yen-Hua, Du, Qingdan, Jiang, Zhihao, King, Gordon J., Collins, Brett M., Wang, Conan K., Craik, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467136/ https://www.ncbi.nlm.nih.gov/pubmed/34577034 http://dx.doi.org/10.3390/molecules26185554 |
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