Deletion of Col15a1 Modulates the Tumour Extracellular Matrix and Leads to Increased Tumour Growth in the MMTV-PyMT Mouse Mammary Carcinoma Model

Basement membrane (BM) zone-associated collagen XV (ColXV) has been shown to suppress the malignancy of tumour cells, and its restin domain can inhibit angiogenesis. In human breast cancer, as well as in many other human carcinomas, ColXV is lost from the epithelial BM zone prior to tumour invasion....

Descripción completa

Detalles Bibliográficos
Autores principales: Martínez-Nieto, Guillermo, Heljasvaara, Ritva, Heikkinen, Anne, Kaski, Hanne-Kaisa, Devarajan, Raman, Rinne, Otto, Henriksson, Charlotta, Thomson, Emmi, von Hertzen, Camilla, Miinalainen, Ilkka, Ruotsalainen, Heli, Pihlajaniemi, Taina, Karppinen, Sanna-Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467152/
https://www.ncbi.nlm.nih.gov/pubmed/34576139
http://dx.doi.org/10.3390/ijms22189978

Ejemplares similares

Ejemplares similares