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Ultrasound and Transcriptomics Identify a Differential Impact of Cisplatin and Histone Deacetylation on Tumor Structure and Microenvironment in a Patient-Derived In Vivo Model of Gastric Cancer

The reasons behind the poor efficacy of transition metal-based chemotherapies (e.g., cisplatin) or targeted therapies (e.g., histone deacetylase inhibitors, HDACi) on gastric cancer (GC) remain elusive and recent studies suggested that the tumor microenvironment could contribute to the resistance. H...

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Detalles Bibliográficos
Autores principales:	Venkatasamy, Aina, Guerin, Eric, Blanchet, Anais, Orvain, Christophe, Devignot, Véronique, Jung, Matthieu, Jung, Alain C., Chenard, Marie-Pierre, Romain, Benoit, Gaiddon, Christian, Mellitzer, Georg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467189/ https://www.ncbi.nlm.nih.gov/pubmed/34575561 http://dx.doi.org/10.3390/pharmaceutics13091485

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