An Inducible and Vascular Smooth Muscle Cell-Specific Pink1 Knockout Induces Mitochondrial Energetic Dysfunction during Atherogenesis

DNA damage and mitochondrial dysfunction are defining characteristics of aged vascular smooth muscle cells (VSMCs) found in atherosclerosis. Pink1 kinase regulates mitochondrial homeostasis and recycles dysfunctional organelles critical for maintaining energetic homeostasis. Here, we generated a new...

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Detalles Bibliográficos
Autores principales: Docherty, Craig K., Bresciani, Jordan, Carswell, Andy, Chanderseka, Amrita, Friel, Elaine, Stasi, Marianna, Mercer, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467198/
https://www.ncbi.nlm.nih.gov/pubmed/34576157
http://dx.doi.org/10.3390/ijms22189993

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