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Development of a Robust Control Strategy for Fixed-Dose Combination Bilayer Tablets with Integrated Quality by Design, Statistical, and Process Analytical Technology Approach

Control strategy and quality by design (QbD) are widely used to develop pharmaceutical products and improve drug quality; however, studies on fixed-dose combination (FDC) bilayer tablets are limited. In this study, the bilayer tablet consisted of high-dose metformin HCl in a sustained-release layer...

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Detalles Bibliográficos
Autores principales:	Chun, Myung-Hee, Kim, Ji Yeon, Park, Eun-Seok, Choi, Du Hyung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467219/ https://www.ncbi.nlm.nih.gov/pubmed/34575519 http://dx.doi.org/10.3390/pharmaceutics13091443

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