Cargando…
Fine Tuning of Cholinesterase and Glutathione-S-Transferase Activities by Organoruthenium(II) Complexes
Cholinesterases (ChEs) show increased activities in patients with Alzheimer’s disease, and remain one of the main therapeutic targets for treatment of this neurodegenerative disorder. A library of organoruthenium(II) complexes was prepared to investigate the influence of their structural elements on...
Autores principales: | Trobec, Tomaž, Sepčić, Kristina, Žužek, Monika Cecilija, Kladnik, Jerneja, Podjed, Nina, Cardoso Páscoa, Catarina, Turel, Iztok, Frangež, Robert |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467340/ https://www.ncbi.nlm.nih.gov/pubmed/34572429 http://dx.doi.org/10.3390/biomedicines9091243 |
Ejemplares similares
-
Novel Organoruthenium(II) Complex C1 Selectively Inhibits Butyrylcholinesterase without Side Effects on Neuromuscular Transmission
por: Trobec, Tomaž, et al.
Publicado: (2023) -
Structural Isomerism and Enhanced Lipophilicity of Pyrithione Ligands of Organoruthenium(II) Complexes Increase Inhibition on AChE and BuChE
por: Kladnik, Jerneja, et al.
Publicado: (2020) -
Exploring pta Alternatives in the Development of Ruthenium–Arene Anticancer Compounds
por: Kljun, Jakob, et al.
Publicado: (2023) -
Organoruthenium Complexes with Benzo-Fused Pyrithiones Overcome Platinum Resistance in Ovarian Cancer Cells
por: Kladnik, Jerneja, et al.
Publicado: (2021) -
Effects of Bioinsecticidal Aegerolysin-Based Cytolytic Complexes on Non-Target Organisms
por: Panevska, Anastasija, et al.
Publicado: (2021)