Curcumin and Nano-Curcumin Mitigate Copper Neurotoxicity by Modulating Oxidative Stress, Inflammation, and Akt/GSK-3β Signaling

Copper (Cu) is essential for multiple biochemical processes, and copper sulphate (CuSO(4)) is a pesticide used for repelling pests. Accidental or intentional intoxication can induce multiorgan toxicity and could be fatal. Curcumin (CUR) is a potent antioxidant, but its poor systemic bioavailability...

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Detalles Bibliográficos
Autores principales: Sarawi, Wedad S., Alhusaini, Ahlam M., Fadda, Laila M., Alomar, Hatun A., Albaker, Awatif B., Aljrboa, Amjad S., Alotaibi, Areej M., Hasan, Iman H., Mahmoud, Ayman M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467357/
https://www.ncbi.nlm.nih.gov/pubmed/34577062
http://dx.doi.org/10.3390/molecules26185591

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