CD18 Antibody Application Blocks Unwanted Off-Target T Cell Activation Caused by Bispecific Antibodies

SIMPLE SUMMARY: Bispecific antibodies are a very effective immunotherapy against different types of cancer since they activate T cells in the presence of tumor cells. However, they can cause severe side effects, such as a systemic inflammation called cytokine release syndrome. We aimed to clarify an...

Descripción completa

Detalles Bibliográficos
Autores principales: Kauer, Joseph, Vogt, Fabian, Hagelstein, Ilona, Hörner, Sebastian, Märklin, Melanie, Maurer, Stefanie, Salih, Helmut R., Jung, Gundram, Zekri, Latifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467378/
https://www.ncbi.nlm.nih.gov/pubmed/34572822
http://dx.doi.org/10.3390/cancers13184596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467378/
https://www.ncbi.nlm.nih.gov/pubmed/34572822
http://dx.doi.org/10.3390/cancers13184596

Ejemplares similares