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CD18 Antibody Application Blocks Unwanted Off-Target T Cell Activation Caused by Bispecific Antibodies
SIMPLE SUMMARY: Bispecific antibodies are a very effective immunotherapy against different types of cancer since they activate T cells in the presence of tumor cells. However, they can cause severe side effects, such as a systemic inflammation called cytokine release syndrome. We aimed to clarify an...
Autores principales: | Kauer, Joseph, Vogt, Fabian, Hagelstein, Ilona, Hörner, Sebastian, Märklin, Melanie, Maurer, Stefanie, Salih, Helmut R., Jung, Gundram, Zekri, Latifa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467378/ https://www.ncbi.nlm.nih.gov/pubmed/34572822 http://dx.doi.org/10.3390/cancers13184596 |
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