Cargando…
PI3K/PTEN/AKT Signaling Pathways in Germ Cell Development and Their Involvement in Germ Cell Tumors and Ovarian Dysfunctions
Several studies indicate that the PI3K/PTEN/AKT signaling pathways are critical regulators of ovarian function including the formation of the germ cell precursors, termed primordial germ cells, and the follicular pool maintenance. This article reviews the current state of knowledge of the functional...
Autores principales: | De Felici, Massimo, Klinger, Francesca Gioia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467417/ https://www.ncbi.nlm.nih.gov/pubmed/34575999 http://dx.doi.org/10.3390/ijms22189838 |
Ejemplares similares
-
To Be or Not to Be a Germ Cell: The Extragonadal Germ Cell Tumor Paradigm
por: De Felici, Massimo, et al.
Publicado: (2021) -
Reprogramming Human Female Adipose Mesenchymal Stem Cells into Primordial Germ Cell-Like Cells
por: Salvatore, Giulia, et al.
Publicado: (2023) -
The piRNA pathway in Drosophila ovarian germ and somatic cells
por: SATO, Kaoru, et al.
Publicado: (2020) -
Expression and possible roles of extracellular signal-related kinases 1-2 (ERK1-2) in mouse primordial germ cell development
por: SORRENTI, Maria, et al.
Publicado: (2020) -
The ovarian reserve as target of insulin/IGF and ROS in metabolic disorder-dependent ovarian dysfunctions
por: Dri, Maria, et al.
Publicado: (2021)