Multiple Myeloma Relapse Is Associated with Increased NFκB Pathway Activity and Upregulation of the Pro-Survival BCL-2 Protein BFL-1

SIMPLE SUMMARY: Multiple myeloma (MM) is a blood cancer that is still incurable because patients become insensitive to available treatments. The cancerous cells in MM misuse a signaling route, called the NFκB pathway, to make MM more difficult to treat. In our study, we used a new method to measure...

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Detalles Bibliográficos
Autores principales: Spaan, Ingrid, van de Stolpe, Anja, Raymakers, Reinier A., Peperzak, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467450/
https://www.ncbi.nlm.nih.gov/pubmed/34572895
http://dx.doi.org/10.3390/cancers13184668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467450/
https://www.ncbi.nlm.nih.gov/pubmed/34572895
http://dx.doi.org/10.3390/cancers13184668

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