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Multiple Myeloma Relapse Is Associated with Increased NFκB Pathway Activity and Upregulation of the Pro-Survival BCL-2 Protein BFL-1
SIMPLE SUMMARY: Multiple myeloma (MM) is a blood cancer that is still incurable because patients become insensitive to available treatments. The cancerous cells in MM misuse a signaling route, called the NFκB pathway, to make MM more difficult to treat. In our study, we used a new method to measure...
Autores principales: | Spaan, Ingrid, van de Stolpe, Anja, Raymakers, Reinier A., Peperzak, Victor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467450/ https://www.ncbi.nlm.nih.gov/pubmed/34572895 http://dx.doi.org/10.3390/cancers13184668 |
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