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Lipid-Based Drug Delivery Systems in Regenerative Medicine
The most important goal of regenerative medicine is to repair, restore, and regenerate tissues and organs that have been damaged as a result of an injury, congenital defect or disease, as well as reversing the aging process of the body by utilizing its natural healing potential. Regenerative medicin...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467523/ https://www.ncbi.nlm.nih.gov/pubmed/34576594 http://dx.doi.org/10.3390/ma14185371 |
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author | Filipczak, Nina Yalamarty, Satya Siva Kishan Li, Xiang Khan, Muhammad Muzamil Parveen, Farzana Torchilin, Vladimir |
author_facet | Filipczak, Nina Yalamarty, Satya Siva Kishan Li, Xiang Khan, Muhammad Muzamil Parveen, Farzana Torchilin, Vladimir |
author_sort | Filipczak, Nina |
collection | PubMed |
description | The most important goal of regenerative medicine is to repair, restore, and regenerate tissues and organs that have been damaged as a result of an injury, congenital defect or disease, as well as reversing the aging process of the body by utilizing its natural healing potential. Regenerative medicine utilizes products of cell therapy, as well as biomedical or tissue engineering, and is a huge field for development. In regenerative medicine, stem cells and growth factor are mainly used; thus, innovative drug delivery technologies are being studied for improved delivery. Drug delivery systems offer the protection of therapeutic proteins and peptides against proteolytic degradation where controlled delivery is achievable. Similarly, the delivery systems in combination with stem cells offer improvement of cell survival, differentiation, and engraftment. The present review summarizes the significance of biomaterials in tissue engineering and the importance of colloidal drug delivery systems in providing cells with a local environment that enables them to proliferate and differentiate efficiently, resulting in successful tissue regeneration. |
format | Online Article Text |
id | pubmed-8467523 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-84675232021-09-27 Lipid-Based Drug Delivery Systems in Regenerative Medicine Filipczak, Nina Yalamarty, Satya Siva Kishan Li, Xiang Khan, Muhammad Muzamil Parveen, Farzana Torchilin, Vladimir Materials (Basel) Review The most important goal of regenerative medicine is to repair, restore, and regenerate tissues and organs that have been damaged as a result of an injury, congenital defect or disease, as well as reversing the aging process of the body by utilizing its natural healing potential. Regenerative medicine utilizes products of cell therapy, as well as biomedical or tissue engineering, and is a huge field for development. In regenerative medicine, stem cells and growth factor are mainly used; thus, innovative drug delivery technologies are being studied for improved delivery. Drug delivery systems offer the protection of therapeutic proteins and peptides against proteolytic degradation where controlled delivery is achievable. Similarly, the delivery systems in combination with stem cells offer improvement of cell survival, differentiation, and engraftment. The present review summarizes the significance of biomaterials in tissue engineering and the importance of colloidal drug delivery systems in providing cells with a local environment that enables them to proliferate and differentiate efficiently, resulting in successful tissue regeneration. MDPI 2021-09-17 /pmc/articles/PMC8467523/ /pubmed/34576594 http://dx.doi.org/10.3390/ma14185371 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Filipczak, Nina Yalamarty, Satya Siva Kishan Li, Xiang Khan, Muhammad Muzamil Parveen, Farzana Torchilin, Vladimir Lipid-Based Drug Delivery Systems in Regenerative Medicine |
title | Lipid-Based Drug Delivery Systems in Regenerative Medicine |
title_full | Lipid-Based Drug Delivery Systems in Regenerative Medicine |
title_fullStr | Lipid-Based Drug Delivery Systems in Regenerative Medicine |
title_full_unstemmed | Lipid-Based Drug Delivery Systems in Regenerative Medicine |
title_short | Lipid-Based Drug Delivery Systems in Regenerative Medicine |
title_sort | lipid-based drug delivery systems in regenerative medicine |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467523/ https://www.ncbi.nlm.nih.gov/pubmed/34576594 http://dx.doi.org/10.3390/ma14185371 |
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