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Lipid-Based Drug Delivery Systems in Regenerative Medicine

The most important goal of regenerative medicine is to repair, restore, and regenerate tissues and organs that have been damaged as a result of an injury, congenital defect or disease, as well as reversing the aging process of the body by utilizing its natural healing potential. Regenerative medicin...

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Detalles Bibliográficos
Autores principales: Filipczak, Nina, Yalamarty, Satya Siva Kishan, Li, Xiang, Khan, Muhammad Muzamil, Parveen, Farzana, Torchilin, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467523/
https://www.ncbi.nlm.nih.gov/pubmed/34576594
http://dx.doi.org/10.3390/ma14185371
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author Filipczak, Nina
Yalamarty, Satya Siva Kishan
Li, Xiang
Khan, Muhammad Muzamil
Parveen, Farzana
Torchilin, Vladimir
author_facet Filipczak, Nina
Yalamarty, Satya Siva Kishan
Li, Xiang
Khan, Muhammad Muzamil
Parveen, Farzana
Torchilin, Vladimir
author_sort Filipczak, Nina
collection PubMed
description The most important goal of regenerative medicine is to repair, restore, and regenerate tissues and organs that have been damaged as a result of an injury, congenital defect or disease, as well as reversing the aging process of the body by utilizing its natural healing potential. Regenerative medicine utilizes products of cell therapy, as well as biomedical or tissue engineering, and is a huge field for development. In regenerative medicine, stem cells and growth factor are mainly used; thus, innovative drug delivery technologies are being studied for improved delivery. Drug delivery systems offer the protection of therapeutic proteins and peptides against proteolytic degradation where controlled delivery is achievable. Similarly, the delivery systems in combination with stem cells offer improvement of cell survival, differentiation, and engraftment. The present review summarizes the significance of biomaterials in tissue engineering and the importance of colloidal drug delivery systems in providing cells with a local environment that enables them to proliferate and differentiate efficiently, resulting in successful tissue regeneration.
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spelling pubmed-84675232021-09-27 Lipid-Based Drug Delivery Systems in Regenerative Medicine Filipczak, Nina Yalamarty, Satya Siva Kishan Li, Xiang Khan, Muhammad Muzamil Parveen, Farzana Torchilin, Vladimir Materials (Basel) Review The most important goal of regenerative medicine is to repair, restore, and regenerate tissues and organs that have been damaged as a result of an injury, congenital defect or disease, as well as reversing the aging process of the body by utilizing its natural healing potential. Regenerative medicine utilizes products of cell therapy, as well as biomedical or tissue engineering, and is a huge field for development. In regenerative medicine, stem cells and growth factor are mainly used; thus, innovative drug delivery technologies are being studied for improved delivery. Drug delivery systems offer the protection of therapeutic proteins and peptides against proteolytic degradation where controlled delivery is achievable. Similarly, the delivery systems in combination with stem cells offer improvement of cell survival, differentiation, and engraftment. The present review summarizes the significance of biomaterials in tissue engineering and the importance of colloidal drug delivery systems in providing cells with a local environment that enables them to proliferate and differentiate efficiently, resulting in successful tissue regeneration. MDPI 2021-09-17 /pmc/articles/PMC8467523/ /pubmed/34576594 http://dx.doi.org/10.3390/ma14185371 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Filipczak, Nina
Yalamarty, Satya Siva Kishan
Li, Xiang
Khan, Muhammad Muzamil
Parveen, Farzana
Torchilin, Vladimir
Lipid-Based Drug Delivery Systems in Regenerative Medicine
title Lipid-Based Drug Delivery Systems in Regenerative Medicine
title_full Lipid-Based Drug Delivery Systems in Regenerative Medicine
title_fullStr Lipid-Based Drug Delivery Systems in Regenerative Medicine
title_full_unstemmed Lipid-Based Drug Delivery Systems in Regenerative Medicine
title_short Lipid-Based Drug Delivery Systems in Regenerative Medicine
title_sort lipid-based drug delivery systems in regenerative medicine
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467523/
https://www.ncbi.nlm.nih.gov/pubmed/34576594
http://dx.doi.org/10.3390/ma14185371
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