Assessing CYP2C8-Mediated Pharmaceutical Excipient-Drug Interaction Potential: A Case Study of Tween 80 and Cremophor EL−35

Pharmaceutical excipients (PEs) are substances included in drug formulations. Recent studies have revealed that some PEs can affect the activity of metabolic enzymes and drug transporters; however, the effects of PEs on CYP2C8 and its interaction potential with drugs remain unclear. In this study, w...

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Detalles Bibliográficos
Autores principales: Wen, Chengming, Hu, Haoyang, Zhang, Wenwen, Liu, Xin, Jiang, Xuehua, Wang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467590/
https://www.ncbi.nlm.nih.gov/pubmed/34575568
http://dx.doi.org/10.3390/pharmaceutics13091492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467590/
https://www.ncbi.nlm.nih.gov/pubmed/34575568
http://dx.doi.org/10.3390/pharmaceutics13091492

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