Cargando…

Human Cystathionine γ-Lyase Is Inhibited by s-Nitrosation: A New Crosstalk Mechanism between NO and H(2)S

The ‘gasotransmitters’ hydrogen sulfide (H(2)S), nitric oxide (NO), and carbon monoxide (CO) act as second messengers in human physiology, mediating signal transduction via interaction with or chemical modification of protein targets, thereby regulating processes such as neurotransmission, blood flo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fernandes, Dalila G. F., Nunes, João, Tomé, Catarina S., Zuhra, Karim, Costa, João M. F., Antunes, Alexandra M. M., Giuffrè, Alessandro, Vicente, João B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467691/ https://www.ncbi.nlm.nih.gov/pubmed/34573023 http://dx.doi.org/10.3390/antiox10091391

Ejemplares similares

Targeting Glutathione and Cystathionine β-Synthase in Ovarian Cancer Treatment by Selenium–Chrysin Polyurea Dendrimer Nanoformulation
por: Santos, Inês, et al.
Publicado: (2019)

Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE)
por: Asimakopoulou, Antonia, et al.
Publicado: (2013)

A cardioprotective insight of the cystathionine γ-lyase/hydrogen sulfide pathway
por: Huang, Steve, et al.
Publicado: (2015)

Dysregulation of cystathionine γ‐lyase promotes prostate cancer progression and metastasis
por: Wang, Yi‐Hsiang, et al.
Publicado: (2019)

Cystathionine γ lyase S-sulfhydrates Drp1 to ameliorate heart dysfunction
por: Wu, Dan, et al.
Publicado: (2022)

Cystathionine γ-Lyase Self-Inactivates by Polysulfidation during Cystine Metabolism
por: Araki, Shoma, et al.
Publicado: (2023)

Expression of Cystathionine β-synthase and Cystathionine γ-lyase in Human Pregnant Myometrium and Their Roles in the Control of Uterine Contractility
por: You, Xing-Ji, et al.
Publicado: (2011)

Enhanced Expression of Cystathionine β-Synthase and Cystathionine γ-Lyase During Acute Cholecystitis-Induced Gallbladder Inflammation
por: Zhang, Li, et al.
Publicado: (2013)

Downregulation of cystathionine β‐synthase and cystathionine γ‐lyase expression stimulates inflammation in kidney ischemia–reperfusion injury
por: Wang, Pengqi, et al.
Publicado: (2014)

Effect of endotoxemia in mice genetically deficient in cystathionine-γ-lyase, cystathionine-β-synthase or 3-mercaptopyruvate sulfurtransferase
por: Ahmad, Akbar, et al.
Publicado: (2016)

Transcriptional regulation of Saccharomyces cerevisiaeCYS3 encoding cystathionine γ-lyase
por: Hiraishi, Hiroyuki, et al.
Publicado: (2008)

Analysis of the sulfur-regulated control of the cystathionine γ-lyase gene of Neurospora crassa
por: Reveal, Brad S, et al.
Publicado: (2012)

Catalytic specificity of the Lactobacillus plantarum cystathionine γ-lyase presumed by the crystallographic analysis
por: Matoba, Yasuyuki, et al.
Publicado: (2020)

Down-Regulated Expression of Cystathionine β-Synthase and Cystathionine γ-Lyase in Varicocele, and Infertile Men: A Case-Control Study
por: Akbarian, Fahimeh, et al.
Publicado: (2022)

Endogenous carbon monoxide downregulates hepatic cystathionine-γ-lyase in rats with liver cirrhosis
por: GUO, SHI-BIN, et al.
Publicado: (2015)

Cystathionine γ-lyase is expressed in human atherosclerotic plaque microvessels and is involved in micro-angiogenesis
por: van den Born, J. C., et al.
Publicado: (2016)

Cystathionine-γ-lyase promotes the metastasis of breast cancer via the VEGF signaling pathway
por: Wang, Lupeng, et al.
Publicado: (2019)

Impact of hyperglycemia on cystathionine-γ-lyase expression during resuscitated murine septic shock
por: Merz, Tamara, et al.
Publicado: (2017)

Structural basis of the inhibition of cystathionine γ‐lyase from Toxoplasma gondii by propargylglycine and cysteine
por: Fernández‐Rodríguez, Carmen, et al.
Publicado: (2023)

N-Acetylcysteine Serves as Substrate of 3-Mercaptopyruvate Sulfurtransferase and Stimulates Sulfide Metabolism in Colon Cancer Cells
por: Zuhra, Karim, et al.
Publicado: (2019)

Transcriptional Regulation of Cystathionine-γ-Lyase in Endothelial Cells by NADPH Oxidase 4-Dependent Signaling
por: Mistry, Rajesh K., et al.
Publicado: (2016)

3-Mercaptopyruvate Sulfurtransferase, Not Cystathionine β-Synthase Nor Cystathionine γ-Lyase, Mediates Hypoxia-Induced Migration of Vascular Endothelial Cells
por: Tao, Beibei, et al.
Publicado: (2017)

Cystathionine- γ-lyase promotes process of breast cancer in association with STAT3 signaling pathway
por: You, Jing, et al.
Publicado: (2017)

Host cystathionine-γ lyase derived hydrogen sulfide protects against Pseudomonas aeruginosa sepsis
por: Renieris, Georgios, et al.
Publicado: (2021)

Cystathionine-γ-lyase drives antioxidant defense in cysteine-restricted IDH1-mutant astrocytomas
por: Cano-Galiano, Andrés, et al.
Publicado: (2021)

Norswertianolin Promotes Cystathionine γ-Lyase Activity and Attenuates Renal Ischemia/Reperfusion Injury and Hypertension
por: Niu, Yaping, et al.
Publicado: (2021)

Deletion of cystathionine-γ-lyase in bone marrow-derived cells promotes colitis-associated carcinogenesis
por: Thanki, Ketan K., et al.
Publicado: (2022)

Cystathionine-γ-lyase overexpression modulates oxidized nicotinamide adenine dinucleotide biosynthesis and enhances neovascularization
por: Kiesworo, Kevin, et al.
Publicado: (2023)

Synthesis of the Indole-Based Inhibitors of Bacterial Cystathionine γ-Lyase NL1-NL3
por: Potapov, Konstantin V., et al.
Publicado: (2023)

Cystathionine-β-synthase: Molecular Regulation and Pharmacological Inhibition
por: Zuhra, Karim, et al.
Publicado: (2020)

Maternal Separation Induces Long-Term Alterations in the Cardiac Oxytocin Receptor and Cystathionine γ-Lyase Expression in Mice
por: Wigger, Daniela C., et al.
Publicado: (2020)

Cystathionine gamma-lyase (CTH) inhibition attenuates glioblastoma formation
por: Peleli, Maria, et al.
Publicado: (2023)

Role for Cystathionine γ Lyase (CSE) in an Ethanol (E)-Induced Lesion in Fetal Brain GSH Homeostasis
por: Patel, Dhyanesh, et al.
Publicado: (2018)

Shexiang Tongxin Dropping Pill Improves Peripheral Microvascular Blood Flow via Cystathionine-γ-Lyase
por: Zhang, Yanda, et al.
Publicado: (2019)

Cystathionine γ-lyase promotes estrogen-stimulated uterine artery blood flow via glutathione homeostasis
por: Bok, Rachael, et al.
Publicado: (2020)

Involvement of 3′,5′‐cyclic inosine monophosphate in cystathionine γ‐lyase‐dependent regulation of the vascular tone
por: Mitidieri, Emma, et al.
Publicado: (2021)

Tanshinone IIA Stimulates Cystathionine γ-Lyase Expression and Protects Endothelial Cells from Oxidative Injury
por: Yan, Qiaojing, et al.
Publicado: (2021)

Cystathionine γ-lyase S-sulfhydrates SIRT1 to attenuate myocardial death in isoprenaline-induced heart failure
por: Wu, Dan, et al.
Publicado: (2023)

Differential Effects of Cystathionine-γ-lyase–Dependent Vasodilatory H(2)S in Periadventitial Vasoregulation of Rat and Mouse Aortas
por: Köhn, Carolin, et al.
Publicado: (2012)

Functional Characterization and Structure-Guided Mutational Analysis of the Transsulfuration Enzyme Cystathionine γ-Lyase from Toxoplasma gondii
por: Maresi, Elena, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_s32l2flrjkaardjcjgk5bj5371