Disorders of the Reproductive Health of Cattle as a Response to Exposure to Toxic Metals

SIMPLE SUMMARY: Heavy metal pollution is common in the environment and can come from natural sources such as forest fires and volcanic eruptions, as well as from anthropogenic sources: mines, smelters, or refineries. These elements are toxic to living organisms and internal organs and can accumulate in living organisms. They can negatively affect both female and male fertility. Chronic exposure of cattle to toxic metals can cause embryotoxicity, disturbances in spermatogenesis, and oocyte development. It is important to monitor environmental pollution with toxic metals. ABSTRACT: The aim of this review is to comprehensively present disorders of the reproductive system in cattle exposed to contact with toxic metals. Toxic metals are a common environmental pollutant and can come from mines, smelters, fossil fuel combustion, or volcanic eruptions. Metals have the ability to bioaccumulate in living organisms, thus contaminating the food chain and may pose a threat to humans. They accumulate mainly in the liver and kidneys, but also in muscles and fat tissue. Toxic metals such as lead (Pb), arsenic (As), mercury (Hg), and cadmium (Cd) have a negative impact on the fertility of animals; they can lead to abortions, premature calving, or oocyte dysfunction. Moreover, in the male reproductive system, they disrupt spermatogenesis, and cause apoptosis of sperm and oxidative damage. The main source of exposure of livestock to toxic metals is through the consumption of feed or contaminated water. It is important to monitor the level of heavy metals in animal products to prevent human poisoning. Toxic metal biomonitoring can be performed by testing urine, blood, milk, plasma, or hair. Chromium (Cr), arsenic (As), and cadmium (Cd) are excreted in the urine, while lead can be detected by examining the blood of animals, while in milk, arsenic (As), cadmium (Cd), nickel (Ni), and lead (Pb) can be detected. Moreover, toxic metals do not biodegrade in the environment. To purify soil and waters, remediation methods, e.g., biological or chemical, should be used.