Cargando…
The Central PXXP Motif Is Crucial for PMAP-23 Translocation across the Lipid Bilayer
PMAP-23, a cathelicidin-derived host defense peptide, does not cause severe membrane permeabilization, but exerts strong and broad-spectrum bactericidal activity. We have previously shown that it forms an amphipathic α-helical structure with a central hinge induced by the PXXP motif, which is implic...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467763/ https://www.ncbi.nlm.nih.gov/pubmed/34575916 http://dx.doi.org/10.3390/ijms22189752 |