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Inhibiting the Unconventionals: Importance of Immune Checkpoint Receptors in γδ T, MAIT, and NKT Cells

SIMPLE SUMMARY: All conventional major histocompatibility complex (MHC)-restricted T cells transiently express immune checkpoint/inhibitory receptors (ICRs) following activation as a means to counter-regulate overactivation. However, tumors promote chronic ICR expression rendering T cells chronicall...

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Detalles Bibliográficos
Autores principales: Catafal-Tardos, Elisa, Baglioni, Maria Virginia, Bekiaris, Vasileios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467786/
https://www.ncbi.nlm.nih.gov/pubmed/34572874
http://dx.doi.org/10.3390/cancers13184647