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An Electrochemical Sensor Based on Amino Magnetic Nanoparticle-Decorated Graphene for Detection of Cannabidiol
For detection of cannabidiol (CBD)—an important ingredient in Cannabis sativa L.—amino magnetic nanoparticle-decorated graphene (Fe(3)O(4)-NH(2)-GN) was prepared in the form of nanocomposites, and then modified on a glassy carbon electrode (GCE), resulting in a novel electrochemical sensor (Fe(3)O(4...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467804/ https://www.ncbi.nlm.nih.gov/pubmed/34578543 http://dx.doi.org/10.3390/nano11092227 |
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author | Zhang, Yi You, Zongyi Hou, Chunsheng Liu, Liangliang Xiao, Aiping |
author_facet | Zhang, Yi You, Zongyi Hou, Chunsheng Liu, Liangliang Xiao, Aiping |
author_sort | Zhang, Yi |
collection | PubMed |
description | For detection of cannabidiol (CBD)—an important ingredient in Cannabis sativa L.—amino magnetic nanoparticle-decorated graphene (Fe(3)O(4)-NH(2)-GN) was prepared in the form of nanocomposites, and then modified on a glassy carbon electrode (GCE), resulting in a novel electrochemical sensor (Fe(3)O(4)-NH(2)-GN/GCE). The applied Fe(3)O(4)-NH(2) nanoparticles and GN exhibited typical structures and intended surface groups through characterizations via transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray powder diffraction (XRD), vibrating sample magnetometer (VSM), and Raman spectroscopy. The Fe(3)O(4)-NH(2)-GN/GCE showed the maximum electrochemical signal for CBD during the comparison of fabricated components via the cyclic voltammetry method, and was systematically investigated in the composition and treatment of components, pH, scan rate, and quantitative analysis ability. Under optimal conditions, the Fe(3)O(4)-NH(2)-GN/GCE exhibited a good detection limit (0.04 μmol L(−1)) with a linear range of 0.1 μmol L(−1) to 100 μmol L(−1) (r(2) = 0.984). In the detection of CBD in the extract of C. sativa leaves, the results of the electrochemical method using the Fe(3)O(4)-NH(2)-GN/GCE were in good agreement with those of the HPLC method. Based on these findings, the proposed sensor could be further developed for the portable and rapid detection of natural active compounds in the food, agricultural, and pharmaceutical fields. |
format | Online Article Text |
id | pubmed-8467804 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-84678042021-09-27 An Electrochemical Sensor Based on Amino Magnetic Nanoparticle-Decorated Graphene for Detection of Cannabidiol Zhang, Yi You, Zongyi Hou, Chunsheng Liu, Liangliang Xiao, Aiping Nanomaterials (Basel) Article For detection of cannabidiol (CBD)—an important ingredient in Cannabis sativa L.—amino magnetic nanoparticle-decorated graphene (Fe(3)O(4)-NH(2)-GN) was prepared in the form of nanocomposites, and then modified on a glassy carbon electrode (GCE), resulting in a novel electrochemical sensor (Fe(3)O(4)-NH(2)-GN/GCE). The applied Fe(3)O(4)-NH(2) nanoparticles and GN exhibited typical structures and intended surface groups through characterizations via transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray powder diffraction (XRD), vibrating sample magnetometer (VSM), and Raman spectroscopy. The Fe(3)O(4)-NH(2)-GN/GCE showed the maximum electrochemical signal for CBD during the comparison of fabricated components via the cyclic voltammetry method, and was systematically investigated in the composition and treatment of components, pH, scan rate, and quantitative analysis ability. Under optimal conditions, the Fe(3)O(4)-NH(2)-GN/GCE exhibited a good detection limit (0.04 μmol L(−1)) with a linear range of 0.1 μmol L(−1) to 100 μmol L(−1) (r(2) = 0.984). In the detection of CBD in the extract of C. sativa leaves, the results of the electrochemical method using the Fe(3)O(4)-NH(2)-GN/GCE were in good agreement with those of the HPLC method. Based on these findings, the proposed sensor could be further developed for the portable and rapid detection of natural active compounds in the food, agricultural, and pharmaceutical fields. MDPI 2021-08-29 /pmc/articles/PMC8467804/ /pubmed/34578543 http://dx.doi.org/10.3390/nano11092227 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Zhang, Yi You, Zongyi Hou, Chunsheng Liu, Liangliang Xiao, Aiping An Electrochemical Sensor Based on Amino Magnetic Nanoparticle-Decorated Graphene for Detection of Cannabidiol |
title | An Electrochemical Sensor Based on Amino Magnetic Nanoparticle-Decorated Graphene for Detection of Cannabidiol |
title_full | An Electrochemical Sensor Based on Amino Magnetic Nanoparticle-Decorated Graphene for Detection of Cannabidiol |
title_fullStr | An Electrochemical Sensor Based on Amino Magnetic Nanoparticle-Decorated Graphene for Detection of Cannabidiol |
title_full_unstemmed | An Electrochemical Sensor Based on Amino Magnetic Nanoparticle-Decorated Graphene for Detection of Cannabidiol |
title_short | An Electrochemical Sensor Based on Amino Magnetic Nanoparticle-Decorated Graphene for Detection of Cannabidiol |
title_sort | electrochemical sensor based on amino magnetic nanoparticle-decorated graphene for detection of cannabidiol |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467804/ https://www.ncbi.nlm.nih.gov/pubmed/34578543 http://dx.doi.org/10.3390/nano11092227 |
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