Local Oral Delivery Agents with Anti-Biofilm Properties for the Treatment of Periodontitis and Peri-Implantitis. A Narrative Review

Despite many discoveries over the past 20 years regarding the etiopathogenesis of periodontal and peri-implant diseases, as well as significant advances in our understanding of microbial biofilms, the incidence of these pathologies continues to rise. For this reason, it was clear that other strategi...

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Autores principales: Elnagdy, Shorouk, Raptopoulos, Michail, Kormas, Ioannis, Pedercini, Alessandro, Wolff, Larry F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467993/
https://www.ncbi.nlm.nih.gov/pubmed/34577132
http://dx.doi.org/10.3390/molecules26185661
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author Elnagdy, Shorouk
Raptopoulos, Michail
Kormas, Ioannis
Pedercini, Alessandro
Wolff, Larry F.
author_facet Elnagdy, Shorouk
Raptopoulos, Michail
Kormas, Ioannis
Pedercini, Alessandro
Wolff, Larry F.
author_sort Elnagdy, Shorouk
collection PubMed
description Despite many discoveries over the past 20 years regarding the etiopathogenesis of periodontal and peri-implant diseases, as well as significant advances in our understanding of microbial biofilms, the incidence of these pathologies continues to rise. For this reason, it was clear that other strategies were needed to eliminate biofilms. In this review, the literature database was searched for studies on locally delivered synthetic agents that exhibit anti-biofilm properties and their potential use in the treatment of two important oral diseases: periodontitis and peri-implantitis.
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spelling pubmed-84679932021-09-27 Local Oral Delivery Agents with Anti-Biofilm Properties for the Treatment of Periodontitis and Peri-Implantitis. A Narrative Review Elnagdy, Shorouk Raptopoulos, Michail Kormas, Ioannis Pedercini, Alessandro Wolff, Larry F. Molecules Review Despite many discoveries over the past 20 years regarding the etiopathogenesis of periodontal and peri-implant diseases, as well as significant advances in our understanding of microbial biofilms, the incidence of these pathologies continues to rise. For this reason, it was clear that other strategies were needed to eliminate biofilms. In this review, the literature database was searched for studies on locally delivered synthetic agents that exhibit anti-biofilm properties and their potential use in the treatment of two important oral diseases: periodontitis and peri-implantitis. MDPI 2021-09-17 /pmc/articles/PMC8467993/ /pubmed/34577132 http://dx.doi.org/10.3390/molecules26185661 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Elnagdy, Shorouk
Raptopoulos, Michail
Kormas, Ioannis
Pedercini, Alessandro
Wolff, Larry F.
Local Oral Delivery Agents with Anti-Biofilm Properties for the Treatment of Periodontitis and Peri-Implantitis. A Narrative Review
title Local Oral Delivery Agents with Anti-Biofilm Properties for the Treatment of Periodontitis and Peri-Implantitis. A Narrative Review
title_full Local Oral Delivery Agents with Anti-Biofilm Properties for the Treatment of Periodontitis and Peri-Implantitis. A Narrative Review
title_fullStr Local Oral Delivery Agents with Anti-Biofilm Properties for the Treatment of Periodontitis and Peri-Implantitis. A Narrative Review
title_full_unstemmed Local Oral Delivery Agents with Anti-Biofilm Properties for the Treatment of Periodontitis and Peri-Implantitis. A Narrative Review
title_short Local Oral Delivery Agents with Anti-Biofilm Properties for the Treatment of Periodontitis and Peri-Implantitis. A Narrative Review
title_sort local oral delivery agents with anti-biofilm properties for the treatment of periodontitis and peri-implantitis. a narrative review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467993/
https://www.ncbi.nlm.nih.gov/pubmed/34577132
http://dx.doi.org/10.3390/molecules26185661
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